ILC Publications Library

The Lobular Breast Cancer Alliance (LBCA) has compiled a reference list of research publications related to lobular breast cancer.

 The list includes studies from 2000 to the present.  We will update this research list periodically. Follow @LobularBCA and #lobular on Twitter to access up-to-date research.

How to use this table: Use the headers on the columns to sort by category. Use the Search function to locate specific study topics. To read a full article with restricted access consult a local medical library or purchase access to the full article. The LBCA can not send or link to restricted articles due to license limitations. Suggestions for additions or changes to this list can be emailed to info@lobularbreastcancer.org for review. Patients utilizing this publications library are encouraged to discuss all studies with their providers.

This document was last updated September, 2020.

Publications and Articles

AUTHORTITLEPUBLICATIONDATEType of ArticleGeneral SubjectSpecific Subject
BlohmerPatient treatment and outcome after breast cancer orbital and periorbital metastases: a comprehensive case series including analysis of lobular versus ductal tumor histologyBreast Cancer Research2020RetrospectiveMetastasisOribital Metastasis
ChristgenDifferential impact of prognostic parameters in hormone receptor-positive lobular breast cancerCancer2020RetrospectiveClinicopathologicalPrognostic biomarkers
GrabenstetterE-cadherin immunohistochemical expression in invasive lobular carcinoma of the breast: correlation with morphology and CDH1 somatic alterationsHuman Pathology2020RetrospectiveClinicopathologicale-Cadherin/CDH1
KurozumiTargetable ERBB2 mutation status is an independent marker of adverse prognosis in estrogen receptor positive, ERBB2 non-amplified primary lobular breast carcinoma: a retrospective in silico analysis of public datasetsBreast Cancer Research2020RetrospectiveCancer BiologyERBB2/Her2 mutations
NarbeThe Distribution of Circulating Tumor Cells Is Different in Metastatic Lobular Compared to Ductal Carcinoma of the Breast-Long-Term Prognostic SignificanceCells2020RetrospectiveMetastasisCirculating Tumor Cells
SreekumarDifferential regulation and targeting of estrogen receptor _ turnover in invasive lobular breast carcinomaEndocrinology2020Laboratory ResearchCancer BiologyEndocrine Response (SERDS)
UlanerHead-to-head evaluation of 18F-FES and 18F-FDG PET/CT in metastatic invasive lobular breast cancerJ Nu Med2020ReviewImagingFES PET/CT
WatanukiImpact of neoadjuvant and adjuvant chemotherapy on invasive lobular carcinoma: A propensity score-matched analysis of SEER dataBreast J2020RetrospectiveClinicopathologicalChemotherapy
AbreuInvasive lobular carcinoma: a rare presentation in the male breastBMJ Case report2016Case ReportClinicopathologicalILC in Male patients
AdachiComparison of clinical outcomes between luminal invasive ductal carcinoma and luminal invasive lobular carcinomaBMC Cancer2016RetrospectiveClinicopathologicalPrognosis
AdachiComparison of sentinel lymph node biopsy between invasive lobular carcinoma and invasive ductal carcinomaBreast Cancer2018RetrospectiveSurgeryLymph node metastasis
AnCdh1 and Pik3ca Mutations Cooperate to Induce Immune-Related Invasive Lobular Carcinoma of the BreastCell Reports2018Laboratory ResearchGenomicsLab Models
AnwarInvasive lobular carcinoma of the breast: Should this be regarded as a chronic disease?Intl J Surg2010RetrospectiveClinicopathologicalPrognosis
ArpinoInfiltrating lobular carcinoma of the breast: tumor characteristics and clinical outcomeBreast Cancer Research2004RetrospectiveClinicopathologicalPrognosis
ArthurMolecular Changes in Lobular Breast Cancers in Response to Endocrine TherapyCancer Res2014RetrospectiveGenomicsAnti-estrogen Therapy
BaePreoperative MR Imaging in Women with Breast Cancer Detected at Screening USRadiology2017RetrospectiveImagingMRI
BagliaAlcohol Intake and Risk of Breast Cancer by Histologic Subtype and Estrogen Receptor Status Among Women Aged 55 to 74 YearsHormones and Cancer2017RetrospectiveRisk FactorsAlcohol use
BajramiE-cadherin/ROS1 inhibitor synthetic lethality in breast cancerCancer Disc2018Laboratory ResearchCancer BiologyE-cadherin
Barroso-SousaDifferences between invasive lobular and invasive ductal carcinoma of the breast: results and therapeutic implicationsAdv Med Onc2016ReviewClinicopathologicalTherapy Response and Resistance
BergDiagnostic accuracy of mammography, clinical examination, US, and MR imaging in preoperative assessment of breast cancerRadiology2004RetrospectiveImagingImaging Modalities
BergeronAn exceptional metaplastic lobular breast carcinoma diagnosed through exome sequencing.J Clin Path2020Case ReportGenomicsMetaplastic Carcinoma
BertozziPrevalence, risk factors, and prognosis of peritoneal metastasis from breast cancerSpringer Plus2015RetrospectiveMetastasisPeritoneal Metastasis
BrunerLoss of E-Cadherin-Dependent Cell_Cell Adhesion and the Development and Progression of CancerCSH Perspectives2018ReviewCancer BiologyE-cadherin
BuchananIs Pleomorphic Lobular Carcinoma Really a Distinct Clinical Entity?J Surg Oncol2008RetrospectiveClinicopathologicalPleomorphic ILC
CaoFrequent amplifications of ESR1, ERBB2 and MDM4 in primary invasive lobular breast carcinomaCancer Letter2019Laboratory ResearchCancer biologyGenomics
CarbogninTargeted next-generation sequencing identifies genomic abnormalities potentially driving the prognosis of early-stage invasive lobular breast carcinoma patients stratified according to a validated clinico-pathological model.Breast2020Laboratory ResearchGenomicsPrognosis
CarcoforoInfiltrating Lobular Carcinoma of the Breast Presenting as Gastrointestinal Obstruction: A Mini ReviewJournal of Cancer2012Case ReportMetastasisGI Metastasis
ChenInvasive lobular carcinoma of the breast: A special histological type compared with invasive ductal carcinomaPLOS One2017RetrospectiveClinicopathologicalPrognosis
Chen21-gene recurrence score and adjuvant chemotherapy decisions in patients with invasive lobular breast cancerBiomarkers in Medicine2018RetrospectiveGenomicsOncotype DX and Chemotherapy
ChristgenLobular breast cancer: molecular basis, mouse and cellular modelsBreast Cancer Research2015ReviewCancer biologyLab Models
ChristgenLobular breast cancer: Clinical, molecular and morphological characteristicsPathology2016ReviewCancer biologyPathology
ChristgenOncogenic PIK3CA Mutations in Lobular Breast Cancer ProgressionGenes Chromosones Cancer2013RetrospectiveGenomicsPIK3CA Mutations
ChristgenSubclonal analysis in a lobular breast cancer with classical and solid growth pattern mimicking a solid_papillary carcinomaJ Patho Clin Res2017Case ReportGenomicsPapillary Carcinoma
ChristofanilliInvasive Lobular Carcinoma Classic Type: Response to Primary Chemotherapy and Survival OutcomesJournal of Clinical Oncology2005RetrospectiveClinicopathologicalChemotherapy
CirielloComprehensive Molecular Portraits of Invasive Lobular Breast CancerCell2015Laboratory ResearchGenomicsGenetic basis of ILC
ConfortiEndocrine-responsive lobular carcinoma of the breast: features associated with risk of late distant recurrenceBreast Cancer Res2019RetrospectiveClinicopathologicalLate recurrence and metastasis
ConlonIs There a Role for Oncotype Dx Testing in Invasive Lobular CarcinomaBreast Journal2015RetrospectiveGenomicsOncotype DX
CoronaManagement of the axilla in breast cancer: outcome analysis in a series of ductal versus lobular invasive cancersBreast Cancer Res Treat2019RetrospectiveClinicopathologicalLymph node metastasis
CorsoCDH1 germline mutations and hereditary lobular breast cancer.Fam Cancer2016ReviewHereditary breast cancerHereditary CDH1 mutation
CostarelliPleomorphic lobular carcinoma: is it more similar to a classic lobular cancer or to a high-grade ductal cancer?Breast Cancer2017RetrospectiveCancer biologyPleomorphic ILC
CrownIntraoperative radiation therapy in early-stage breast cancer: Presence of lobular features is not associated with increased rate of requiring additional therapy.Am J Surg2019RetrospectiveSurgeryIntra-operative Radiation
Da RosHER2-positive lobular versus ductal carcinoma of the breast: pattern of first recurrence and molecular insights.Clin Breast Cancer2018RetrospectiveClinicopathologicalHer 2 Mutation
DabbsLobular versus ductal breast neoplasms: the diagnostic utility of p120 cateninAm J Surg Path2007RetrospectiveClinicopathologicalP120-Catenin
DaniaAssociations of race and ethnicity with risk of developing invasive breast cancer after lobular carcinoma in situBreast Cancer Res2019RetrospectiveRisk FactorsRace/ethinicity risk after LCIS
DashevskyAppearance of untreated bone metastases from breast cancer on FDG PET/CT: Importance of histologic subtypeEur J Nucl Med Mol Imaging2015RetrospectiveImagingBone Metastases
de groot_E_catenin is a candidate tumor suppressor for the development of E_cadherin_expressing lobular_type breast cancerJ Pathology2018Laboratory ResearchCancer BiologyE-cadherin
de NonnevilleAdjuvant Chemotherapy in Lobular Carcinoma of the Breast: A Clinicopathological Score Identifies High-Risk Patient With Survival BenefitBreast Cancer Res2019RetrospectiveClinicopathologicalChemotherapy
DelpechClinical benefit from neoadjuvant chemotherapy in oestrogen receptor-positive invasive ductal and lobular carcinomasBritish Journal of Cancer2013RetrospectiveClinicopathologicalChemotherapy
DeniziatERBB2 mutations associated with solid variant of high-grade invasive lobular breast carcinomasOncotarget2016RetrospectiveGenomicsHER2 Mutations
DerksenMammary-specific inactivation of E-cadherin and p53 impairs functional gland development and leads to pleomorphic invasive lobular carcinoma in miceDis Model Mech2011Laboratory ResearchCancer BiologyLab models of ILC
DerksonSomatic inactivation of E-cadherin and p53 in mice leads to metastatic lobular mammary carcinoma through induction of anoikis resistance and angiogenesisCancer Cell2006Laboratory ResearchCancer BiologyLab models of ILC/Metastases
DesmedtGenomic Characterization of Primary Invasive Lobular Breast CancerJournal of Clinical Oncology2016Laboratory ResearchGenomicsGenetic basis of ILC
DesmedtESR1 mutations in metastatic lobular breast cancer patientsnpj Breast Cancer2019RetrospectiveGenomicsESR1 Mutation
DesmedtImmune Infiltration in Invasive Lobular Breast CancerJ Natl Cancer Inst.2018RetrospectiveCancer biologyImmunology
DessauvagieInvasive lobular carcinoma of the breast: assessment of proliferative activity using automated Ki-67 immunostainingPathology2019RetrospectiveClinicopathologicalKi67
DiPiroLobular breast cancer: patterns of intraabdominal metastatic spread on imaging and prognosticsignificance.Abdom Radiology2019RetrospectiveClinicopathologicalAbdominal Metastasis
DitchiLow risk of invasive lobular carcinoma of the breast in carriers of BRCA1 and TP53 (Li-Fraumeni syndrome) germline mutationsBreast Journal2018RetrospectiveHereditary breast cancerBRCA1/2 and p53 mutation
DixonInvasive lobular carcinoma: response to neoadjuvant letrozole therapyBreast Cancer Res Treat2011RetrospectiveClinicopathologicalAnti-estrogen Therapy
DonaldsonBreast cancer risk associated with atypical hyperplasia and lobular carcinoma in situ initially diagnosed on core-needle biopsyCancer2018RetrospectiveRisk FactorsLCIS/Hyperplasia
DossusLobular breast cancer: incidence and genetic and non-genetic risk factorsBreast Cancer Research2015ReviewGenomicsRisk and incidence
DuKey regulators of lipid metabolism drive endocrine resistance in invasive lobular breast cancerBreast Cancer Research2018Laboratory ResearchCancer biologyAnti-estrogen resistance
EngstromInvasive lobular breast cancer: the prognostic impact of histopathological grade, E-cadherin and molecular subtypesHistopathology2015RetrospectiveClinicopathologicalPrognosis
FeltsAn Analysis of Oncotype DX Recurrence Scores and Clinicopathologic Characteristics in Invasive Lobular Breast Cancer.Breast j2017RetrospectiveGenomicsOncotype DX
FranzoiLeptomeningeal carcinomatosis in patients with breast cancer.Crit Rev Oncol Hematol2019ReviewMetastasisLeptomeningal Metastasis
GainerInvasive Lobular Carcinoma Predicts Micrometastasis in Breast CancerJournal or Surgical Research2012Laboratory ResearchCancer biologyMetastasis
GaoCDK4/6 inhibitor treatment for patients with hormone receptor-positive, HER2-negative, advanced or metastatic breast cancerLancet Oncol2019RetrospectiveClinicopathologicalCDK4/6 inhibitor response
GatzaAnother Breast Cancer Entity Confirmed: Genomics of Invasive Lobular Breast CancerJournal of Clinical Oncology2016ReviewGenomicsGenomics of ILC
GuiuInvasive lobular breast cancer and its variants: how special are they for systemic therapy decisions?Crit Rev Onco Hematology2014ReviewClinicopathologicalTherapy Response and Resistance
GuvenSentinel Lymph Node Metastasis in Invasive Lobular Carcinoma of the BreastEuropean Journal Br Helath2018RetrospectiveMetastasisLymph node Metastasis
HaBreast MR Imaging before Surgery: Outcomes in Patients with Invasive Lobular Carcinoma by Using Propensity Score MatchingRadiology2018RetrospectiveImagingMRI
HansfordHereditary Diffuse Gastric Cancer Syndrome -CDH1 Mutations and BeyondJama Oncol2015RetrospectiveHereditary breast cancerHereditary CDH1 mutation
HarrellEstrogen induces c-Kit and an aggressive phenotype in a model of invasive lobular breast cancerOncogeniesis2017Laboratory ResearchCancer BiologyEstrogen signaling
HarrisonGenomic profiling of pleomorphic and florid lobular carcinoma in situ reveals highly recurrent ERBB2 and ERRB3 alterationsMod Pathol2019RetrospectiveGenomicsHer2 mutation in Pleomorphic and Florid LCIS
HeDistant Metastatic Disease Manifestations in Infiltrating Lobular Carcinoma of the BreastAJR2014ReviewMetastasisMetastatic Sites
HoganComparison of 18F-FDG PET/CT for Systemic Staging of Newly Diagnosed Invasive Lobular Carcinoma Versus Invasive Ductal CarcinomaJ Nucl Med2015RetrospectiveImagingFDG PET/CT
HornsveldRestraining FOXO3-dependent transcriptional BMF activation underpins tumour growth and metastasis of E-cadherin-negative breast cancerCell Death Diff2016Laboratory ResearchCancer BiologyMetastasis /E-cadherin
HoussamiMeta-analysis of pre-operative magnetic resonance imaging (MRI) and surgical treatment for breast cancerBreast Canc Res Treat2017RetrospectiveImagingMRI
HuAdjuvant chemotherapy could not bring survival benefit to HR-positive, HER2-negative, pT1b-c/N0_1/M0 invasive lobular carcinoma of the breast: a propensity score matching study based on SEER databaseBMC Cancer2020RetrospectiveClinicopathologicalChemotherapy
InoueSpecific sites of metastases in invasive lobular carcinoma: a retrospective cohort study of metastatic breast cancerBreast Cancer2017RetrospectiveMetastasisMetastatic Sites
IorfidaInvasive lobular breast cancer: subtypes and outcomeBreast Cancer Res Treat2012RetrospectiveClinicopathologicalPrognosis
IshidaPleomorphic lobular carcinoma in a male breast: a case report with review of the literatureInt J Clin Exp Pathol2013Case ReportClinicopathologicalILC in Male patients
JacobsIssues Affecting the Loco-regional and Systemic Management of Patients with Invasive Lobular Carcinoma of the BreastThe Breast Journal2015ReviewClinicopathologicalTherapy Response and Resistance
JohnsonLobular breast cancer series: imagingBreast Cancer Research2015ReviewImagingImaging Modalities
KarjolBladder Metastasis from Breast Cancer: A Systematic ReviewCereus202ReviewClinicopathologicalBladder Metastasis
KatzPrimary systemic chemotherapy of invasive lobular carcinoma of the breastLancet2007ReviewClinicopathologicalChemotherapy
KlarenbeekResponse of metastatic mouse invasive lobular carcinoma to mTOR inhibition is partly mediated by the adaptive immune systemOncoimmunology2020Laboratory researchCancer BiologyTherapy Response (PI3K/mTOR)
KorhonenThe impact of lobular and ductal breast cancer histology on the metastatic behavior and long term survival of breast cancer patientsThe Breast2013RetrospectiveClinicopathologicalMetastasis
KutasovicBreast cancer metastasis to gynaecological organs: a clinico_pathological and molecular profiling studyJ Pathol Clin Res2019RetrospectiveGenomicsGynocological Metastasis
LaenkholmPopulation-based Study of Prosigna-PAM50 and Outcome Among Postmenopausal Women With Estrogen Receptor-positive and HER2-negative Operable Invasive Lobular or Ductal Breast Cancer.Clin Breast Cancer2020RetrospectiveGenomicsBiomarkers of prognosis/PAM50
LanglandsContralateral breast cancer: incidence according to ductal or lobular phenotype of the primaryClinical Radiology2016RetrospectiveClinicopathologicalContralateral Breast Cancer
LevineFGFR4 overexpression and hotspot mutations in metastatic ER+ breast cancer are enriched in the lobular subtypeNPJ Breast Cancer2019Laboratory ResearchGenomicsMetastasis
LiHormone replacement therapy in relation to risk of lobular and ductal breast carcinoma in middle-aged women.Cancer2000RetrospectiveRisk FactorsHormone Replacement Therapy
LiChanging Incidence Rate of Invasive Lobular Breast Carcinoma among Older WomenCancer2000RetrospectiveRisk FactorsIncidence
LiaoThe Clinicopathological Features and Survival Outcomes of Different Histological Subtypes in Triple-negative Breast CancerJ Cancer2018RetrospectiveClinicopathologicalTriple-negative ILC
LienFrequent alterations of HER2 through mutation, amplification, or overexpression in pleomorphic lobular carcinoma of the breast.Breast Canc Res Treat2017RetrospectiveGenomicsHER2 mutation
LoganMolecular drivers of lobular carcinoma in situBreast Cancer Research2015ReviewCancer biologyLCIS
LokadasanMetastatic lobular carcinoma of breast mimics primary cervix carcinoma: two case reports and a review of the literatureecancermedicalscience2015Case ReportMetastasisCervical Metastasis
LopezInvasive Lobular Carcinoma of the Breast: Spectrum of Mammo- graphic, US, and MR Imaging FindingsRadiographics2009ReviewImagingImaging modalities
LuvetaInvasive Lobular Breast Cancer as a Distinct Disease: Implications for Therapeutic StrategyOncol and Therapy2019ReviewCancer BiologyGenomics and Treatment
MamtaniLobular Breast Cancer Different Disease, Different AlgorithmsSurgical Oncol Cinics2018ReviewClinicopathologicalGenomics of ILC
MamtaniLobular Histology Does Not Predict the Need for Axillary Dissection Among ACOSOG Z0011-Eligible Breast CancerAnn Surg Oncol2019RetrospectiveSurgeryLymph Node Metastasis
MannMRI compared to conventional diagnostic work-up in the detection and evaluation of invasive lobular carcinoma of the breastBreast Cancer Res Treat2008ReviewImagingMRI
MarmorRelative Effectiveness of Adjuvant Chemotherapy for Invasive Lobular Compared With Invasive Ductal Carcinoma of the BreastCancer2017RetrospectiveClinicopathologicalChemotherapy
MathewDistinct Pattern of Metastases in Patients with Invasive Lobular Carcinoma of the BreastGeburtshilfe Frauenheilkd2017RetrospectiveMetastasisMetastatic sites
MathieuThe poor responsiveness of infiltrating lobular breast carcinomas to neoadjuvant chemotherapy can be explained by their biological profileEur J Cancer2004RetrospectiveClinicopathologicalChemotherapy
McCart ReedMixed ductal-lobular carcinomas: evidence for progression from ductal to lobular morphologyJ Pathology2018RetrospectiveCancer biologyMixed ductal-lobular
McCart ReedLobSig is a multigene predictor of outcome in invasive lobular carcinomaNPJ Breast Cancer2019Laboratory ResearchGenomicsGene signatures
McCart ReedAn epithelial to mesenchymal transition programme does not usually drive the phenotype of invasive lobular carcinomasJ Pathology2015Laboratory ResearchCancer Biologye-Cadherin/EMT
McCart ReedInvasive lobular carcinoma of the breast: morphology, biomarkers and ̍omicsBreast Cancer Research2015ReviewCancer biologyGenomics of ILC
McLemoreBreast cancer: presentation and intervention in women with gastrointestinal metastasis and carcinomatosisAnn Surg Onc2005RetrospectiveMetastasisGI Metastasis
Metzger-FilhoMagnitude of trastuzumab benefit in patients with HER2-positive, invasive lobular breast carcinoma: results from the HERA trialJournal of Clinical Oncology2013RetrospectiveClinicopathologicalHER2-targeted therapy
Metzger-FilhoRelative Effectiveness of Letrozole Compared With Tamoxifen for Patients With Lobular Carcinoma in the BIG 1-98 TrialJournal of Clinical Oncology2015RetrospectiveClinicopathologicalAnti-estrogen therapy
Metzger-FilhoGenomic grade adds prognostic value in invasive lobular carcinomaAnn Onc2013RetrospectiveGenomicsGene Signatures
Metzger-FilhoMixed Invasive Ductal and Lobular Carcinoma of the Breast: Prognosis and the Importance of Histologic GradeThe Oncologist2018RetrospectiveClinicopathologicalMixed ILC/IDC
MichautIntegration of genomic, transcriptomic and proteomic data identifies two biologically distinct subtypes of invasive lobular breast cancerSci Rep2016Laboratory ResearchGenomicsGenetic basis of ILC
MontagnaLobular Metastatic Breast Cancer Patients With Gastrointestinal Involvement: Features and OutcomesClinical Breast Cancer2018RetrospectiveMetastasisMetastatic sites
MontanaghInvasive lobular carcinoma with papillary features: A newly described variant that poses a difficult histologic differential diagnosis.Breast J2020Case ReportClinicopathologalPapillary Carcinoma
MotenCharacterizing lobular carcinoma of the male breast using the SEER database.J surg Res2013RetrospectiveClinicopathologicalILC in Male patients
MukhtarBreast Conservation and Negative Margins in Invasive Lobular Carcinoma: The Impact of Oncoplastic Surgery and Shave Margins in 358 PatientsAnnals of Surgical Oncol2018RetrospectiveSurgerySurgical methods
MukhtarMitotic Score and Pleomorphic Histology in Invasive Lobular Carcinoma of the Breast: Impact on Disease-Free SurvivalBreast Cancer Res Treat2020RetrospectiveClinicopathologicalPleomorphic ILC
NagleLoss of E-cadherin Enhances IGF1_IGF1R Pathway Activation and Sensitizes Breast Cancers to Anti-IGF1R/InsR InhibitorsClinical Cancer Research2018Laboratory ResearchCancer biologyCell signaling
NarbeInvasive lobular carcinoma of the breast: long-term prognostic value of Ki67 and histological grade, alone and in combination with estrogen receptorSpringer Plus2014RetrospectiveClinicopathologicalKi67
OesterreichOpening the Door for Immune Oncology Studies in Invasive Lobular Breast CancerJ Natl Cancer Inst.2018CommentaryCancer biologyImmunology
OliveraEvolving concepts in breast lobular neoplasia and invasive lobular carcinoma, and their impact on imaging methodsInsights Imaging2014ReviewImagingImaging modalities
OrvietoClinicopathologic characteristics of invasive lobular carcinoma of the breastCancer2008RetrospectiveClinicopathologicalPrognosis
PatelValue Added of Preoperative Contrast-Enhanced Digital Mammography in Patients With Invasive Lobular Carcinoma of the BreastClinical Breast Cancer2018RetrospectiveImagingMammography methods
Perez-GarciaEfficacy of Single-Agent Chemotherapy for Patients with Advanced Invasive LobularCarcinomaThe Oncologist2018RetrospectiveClinicopathologicalChemotherapy
PestalozziDistinct Clinical and Prognostic Features of Infiltrating Lobular Carcinoma of the Breast: Combined Results of 15 International clinical trialsJ Clin Oncol2008RetrospectiveClinicopathologicalPrognosis
PetridisFrequency of Pathogenic Germline Variants in CDH1, BRCA2, CHEK2, PALB2, BRCA1, and TP53 in Sporadic Lobular Breast CancerCancer Epidemiol Biomark2019RetrospectiveGenomicsGenetic basis of ILC
PhalakSupplemental ultrasound screening in patients with a history of lobular neoplasiaThe Breast Journal2018RetrospectiveImagingLobular Neoplasia
RaapHigh frequency of lobular breast cancer in distant metastases to the orbitCancer Med2015RetrospectiveMetastasisOribital Metastasis
RaapLobular carcinoma in situ and invasive lobular breast cancer are characterized by enhanced expression of transcription factor AP-2_.Lab Invest2017Laboratory ResearchCancer BiologyGenomics of ILC
RakhaInvasive lobular carcinoma of the breast: response to hormonal therapy and outcomesEur J Cancer2008RetrospectiveClinicopathologicalAnti-estrogen therapy
RigginsERR_ mediates Tamoxifen resistance in novel models of invasive lobular breast cancerCancer Res2008Laboratory ResearchCancer biologyAnti-estrogen resistance
Rosa-RosaHigh Frequency of ERBB2 Activating Mutations in Invasive Lobular Breast Carcinoma with Pleomorphic FeaturesCancers2019RetrospectiveCancer biologyHER2 mutation in PLC
RossRelapsed Classic E-Cadherin (CDH1)_Mutated Invasive Lobular Breast Cancer Shows a High Frequency of HER2 (ERBB2) Gene MutationsClinical Cancer Research2013RetrospectiveGenomicsHER2 mutation in ILC
SahinInvasive Pleomorphic Lobular Histology Is an Adverse Prognostic Factor on Survival in Patients with Breast CancerAm Surg2017RetrospectiveClinicopathologicalPleomorphic ILC
SawyerGenetic Predisposition to In Situ and Invasive Lobular Carcinoma of the BreastPLOS2014RetrospectiveGenomicsGenetic Basis of ILC/LCIS
SchackmannCytosolic p120-catenin regulates growth of metastatic lobular carcinoma through Rock1-mediated anoikis resistanceJ Clin Invest2011Laboratory ResearchCancer BiologyP120-Catenin
SchipperTruncated ASPP2 Drives Initiation and Progression of Invasive Lobular Carcinoma via Distinct MechanismsCancer Res2020Laboratory ResearchCancer BiologyLab Models
SelinkoRole of sonography in diagnosing and staging invasive lobular carcinomaJ Clin Ultrasound2004RetrospectiveImagingImaging Methods
SengerInvasive lobular carcinoma of the male breast _ a systematic review with an illustrative case studyBreast Cancer2017Case ReportClinicopathologicalILC in male patients
ShahPIK3CA mutations are common in lobular carcinoma in situ, but are not a biomarker of progressionBreast Cancer Research2017RetrospectiveGenomicsPIK3CA mutations in LCIS
ShamirGenetic analysis of pleomorphic and florid lobular carcinoma in situ variants: frequent ERBB2/ERBB3 alterations and clonal relationship to classic lobular carcinoma in situ and invasivelobular carcinomaMod Pathol2020RetrospectiveGenomicsHer2 mutation in Pleomorphic and Florid LCIS/ILC
ShraderHereditary diffuse gastric cancer: association with lobular breast cancerFam Cancer2008Case ReportClinicopathologicalHerditary CDH1 mutation
SikoraInvasive lobular carcinoma of the breast: Patient response to systemic endocrine therapy and hormone response in model systemsSteroids2012ReviewCancer biologyAnti-estrogen therapy
SikoraInvasive lobular carcinoma cell lines are characterized by unique estrogen-mediated gene expression patterns and altered tamoxifen responseCancer Resarch2014Laboratory ResearchCancer biologyAnti-estrogen response and resistance
SikoraWNT4 mediates estrogen receptor signaling and endocrine resistance in invasive lobular carcinoma cell linesBreast Cancer Research2016Laboratory ResearchCancer biologyAnti-estrogen response and resistance
SingletaryTreatment Trends in Early-Stage Invasive Lobular CarcinomaAnn Surgery2005RetrospectiveSurgerySurgical Methods
SledgeCollective Wisdom: Lobular Carcinoma of the BreastASCO2016ReviewCancer biologyTherapy response and resistance
SokolLoss of function of NF1 is a mechanism of acquired resistance to endocrine therapy in lobular breast cancerAnn Oncol2018Laboratory ResearchGenomicsAnti-estrogen resistance
StangeHigh-Resolution Genomic Profiling Reveals Association of Chromosomal Aberrations on 1q and 16p with Histologic and Genetic Subgroups of IBC cell linesClinical Cancer Research2006RetrospectiveGenomicsGenomics of ILC
Strasser-WeipplOutcomes in women with invasive ductal or invasive lobular early stage breast cancer treated with anastrozole or exemestaneEuropean Journal of Cancer2018RetrospectiveClinicopathologicalAnti-estrogen therapy
SwitzerCase series of 21 patients with extrahepatic metastatic lobular breast carcinoma to the gastrointestinal tractCancer Treat Comm2015Case ReportMetastasisGI Metastasis
TalmanInvasive lobular breast cancer. Prognostic significance of histological malignancy gradingActa Onc2006RetrospectiveClinicopathologicalPrognosis
TamarisaThe impact of chemotherapy sequence on survival in node-positive invasive lobular carcinomaJ Surg Onco2019RetrospectiveClinicopathologicalChemotherapy
TasdemirComprehensive phenotypic characterization of human invasive lobular carcinoma cell lines in 2D and 3D culturesCancer Resarch2018Laboratory ResearchCancer biologyLab models
Tenhagenp120-Catenin Is Critical for the Development of Invasive Lobular Carcinoma in MiceJ Mamm Gland Biol Neo2016Laboratory ResearchCancer BiologyP120 Catenin
TeoE-cadherin loss induces targetable autocrine activation of growth factor signalling in lobular breast cancerScientific Reports2018Laboratory ResearchCancer biologyCell signaling
ThomasInvasive lobular breast cancer: A review of pathogenesis, diagnosis, management, and future directions of early stage diseaseSemin Oncol2019ReviewClinicopathologicalNeoadjuvant Therapy
ThorntonNeoadjuvant Endocrine Therapy Versus Neoadjuvant Chemotherapy in Node-Positive Invasive Lobular CarcinomaAnn Surg Oncol2019RetrospectiveClinicopathologicalTherapy Response
TilleTumor-infiltrating lymphocytes are associated with poor prognosis in invasive lobular breast carcinomaMod Pathol2020RetrospectiveCancer BiologyImmunology
TruinDifferences in Response and Surgical Management with Neoadjuvant Chemotherapy in Invasive Lobular Versus Ductal Breast CancerAnnals of Surgical Oncol2016RetrospectiveClinicopathologicalNeoadjuvent Chemotherapy
UlanerProspective Clinical Trial of 18F-Fluciclovine PET/CT for Determining the Response to Neoadjuvant Therapy in IDC and ILCJournal of Nuclear Medicine2017ProspectiveImaging18 F-Fluciclovine PET/CT
van de VenNuclear p120-catenin regulates the anoikis resistance of mouse lobular breast cancer cells through Kaiso-dependent Wnt11 expressionDis Model Mech2015Laboratory ResearchCancer BiologyP120 Catenin
van de WaterInfluence of semi-quantitative oestrogen receptor expression on adjuvant endocrine therapy efficacy in ductal and lobular breast cancerEur J Cancer2012RetrospectiveClinicopathologicalAnti-estrogen Therapy
van der PostHereditary diffuse gastric cancer: updated clinical guidelines with an emphasis on germline CDH1 mutation carriersJ Med Genet2015ReviewRisk FactorsHereditary CDH1 Mutation
VargasPleomorphic lobular carcinoma of the breast: molecular pathology and clinical impactFuture Oncol2009ReviewGenomicsPleomorphic
Venema18F-FES PET Has Added Value in Staging and Therapy Decision Making in Patients With Disseminated Lobular Breast Cancer.Clin Nucl Med2017Laboratory ResearchImagingFES PET
VlugNuclear localization of the transcriptional coactivator YAP is associated with invasive lobular breast cancerCell Oncol2013Laboratory ResearchCancer BiologyCell Signaling
WalshBET Inhibition as a Rational Therapeutic Strategy for Invasive Lobular Breast Cancer.Clin Can Res2019Laboratory ResearchCancer BiologyNovel therapeutics
WangThe Distribution and Outcomes of the 21-Gene Recurrence Score in T1-T2N0 Estrogen Receptor-Positive Breast Cancer With Different Histologic SubtypesFrontiers in Genetics2018RetrospectiveGenomicsOncotype DX
WilliamsDifferences in race, molecular and tumor characteristics among women diagnosed with invasive ductal and lobular breast carcinomasCancer Causes2019RetrospectiveClinicopathologicalRacial Differences in ILC vs IDC
WinstonMetastatic Lobular Carcinoma of the Breast: Patterns of Spread in the Chest, Abdomen, and Pelvis on CTAJR2000RetrospectiveMetastasisMetastatic sites
WongEvaluating the Impact of Breast Density on Preoperative MRI in Invasive Lobular CarcinomaJ Am Coll Surg2018RetrospectiveImagingMRI
XiaoScientific reports2017RetrospectiveClinicopathologicalMixed IDC/ILC
XicolaClinical features and cancer risk in families with pathogenic CDH1 variants irrespective of clinical criteriaClinical features and cancer risk in families with pathogenic CDH1 variants irrespective of clinical criteriaJ Med Genet2019RetrospectiveClinicopathologicalGenetic basis of ILC
XinA review of invasive lobular carcinoma of the breast: Should it be treated like invasive ductal carcinoma?Integr Cancer Sci Therapy2007ReviewClinicopathologicalPrognosis
YuClassical-type invasive lobular carcinoma with HER2 overexpression: clinical, histologic, and hormone receptor characteristicsAm J Clinical Path2011Case ReportCancer biologyHER2 in ILC
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