| Sottnik | Altered MDC1 Interactions and Dysfunctional DNA Repair in Lobular Breast Cancer Confers Sensitivity to PARP Inhibition | Cancer Research | 2026 | Lab Research | Cancer Biology | DNA repair dysfunction and MDC1–ER interaction in invasive lobular carcinoma; homologous recombination impairment and PARP inhibitor sensitivity in ILC models |
| Marra | Tracking response to neoadjuvant systemic therapy through circulating tumor DNA analysis in breast cancer | npj Breast Cancer | 2026 | Article | Tumor Biomarkers | Circulating tumor DNA (ctDNA) for monitoring response to neoadjuvant systemic therapy and predicting relapse risk in stage II–III breast cancer |
| Safonov | Homologous recombination deficiency and hemizygosity drive resistance in breast cancer | Nature | 2026 | Article | Genomics | HRD; BRCA2 and RB1 loss; CDK4/6 inhibitor resistance; PARP inhibitor sensitivity |
| Aouad | Preclinical models of breast cancer metastasis: strengths, limitations, and clinical relevance | npj Breast Cancer | 2026 | Review | Metastasis | Preclinical models of breast cancer metastasis, including ILC-relevant models; xenografts; GEMMs; PDX; dormancy; organ tropism; tumor microenvironment |
| Flaherty | LOX Inhibition Disrupts a Collagen–Integrin–MYC Axis to Suppress Progression of Invasive Lobular Carcinoma | Cancer Research | 2026 | Lab Research | Cancer Biology | Invasive lobular carcinoma; extracellular matrix (collagen) dependency; LOX inhibition (PXS-5505); integrin signaling (ITGAV/ITGB5); MYC/NF-κB/AP-1 pathways; intraductal xenograft models |
| Corso | Invasive lobular and ductal breast cancers: a systematic review and metanalysis in association with BRCA1/2 mutation status | European Journal of Cancer | 2026 | Review | Epidemiology | Genomics; BRCA1/2 mutation prevalence; ILC vs IDC differences; hereditary risk; genetic testing; subtype-specific risk patterns |
| Switalla | A prospective single-arm pilot study evaluating [F-18]fluoroestradiol dedicated breast PET in invasive lobular carcinoma after neoadjuvant endocrine therapy | Breast Cancer Research | 2026 | Prospective | Imaging | FES-PET; ER imaging; neoadjuvant endocrine therapy; ILC imaging response; staging and detection |
| Mukhtar | Tailoring Management for Invasive Lobular Carcinoma: Imaging, Surgical Treatment, and Systemic Therapy Considerations | American Society of Clinical Oncology Educational Book | 2026 | Review | Clinicopathological | ILC management; imaging; surgical treatment; systemic therapy |
| Quinn | World Health Organization classification of tumours of the breast 6th edition 2026 | Histopathology | 2026 | Review | Clinicopathological | WHO breast tumour classification; ILC with extracellular mucin; diagnostic classification; biomarkers |
| Cody | Quantitative and qualitative patient-reported analysis of misdiagnosis and/or late diagnosis of metastatic lobular cancer | npj Breast Cancer | 2026 | Lab Research | Metastasis | Misdiagnosis and delayed diagnosis of metastatic ILC; patient-reported experiences; imaging and surveillance |
| De Laurentiis | 119 Progression-Free Survival (PFS) and Overall Survival (OS) Results From the Phase 3 MONALEESA-3 Trial of Postmenopausal Patients With Hormone Receptor–Positive (HR+)/Human Epidermal Growth Factor Receptor 2–Negative (HER2−) Advanced Breast Cancer (ABC) Treated With Ribociclib (RIB) + Fulvestrant (FUL): A Subgroup Analysis of Patients With Invasive Lobular Carcinoma (ILC) | Miami Breast Cancer Conference Abstracts Supplement | 2026 | Conference Abstract | Clinical Trials | MONALEESA-3 ILC subgroup; ribociclib plus fulvestrant; progression-free and overall survival |
| Rima | Multidimensional Cellular Micro-Compartments to Model Invasive Lobular Carcinoma Dormancy | Advanced Healthcare Materials | 2026 | Lab Research | Metastasis | ILC dormancy; disseminated tumor cell dormancy; anti-estrogen resistance; microfluidic disease modeling |
| Csaky | Invasive lobular carcinoma: Shining a light on the second most prevalent type of breast cancer | Nurse Practitioner | 2026 | Review | Clinicopathological | ILC vs IDC differences; epidemiology; pathology; nursing/clinical awareness |
| Abeles | Omission of Axillary Surgery in Patients with Invasive Lobular Carcinoma of the Breast: Rates of Nodal Involvement in Clinically Node Negative Patients and Impact on Recurrence in a Single Institution Analysis | Ann Surg Oncol | 2026 | Lab Research | Surgery | Axillary surgery omission; sentinel lymph node biopsy; nodal involvement; clinically node-negative ILC; recurrence |
| Fasano | Clinical Impact and Outcomes of Neoadjuvant Systemic Therapy for Invasive Lobular Carcinoma | Ann Surg Oncol | 2026 | Lab Research | Treatment | Neoadjuvant systemic therapy; neoadjuvant chemotherapy (NAC); neoadjuvant endocrine therapy (NET); pathologic complete response; sentinel lymph node biopsy; survival and axillary recurrence |
| Djerroudi | Invasive Lobular Carcinoma: Clinicopathologic and Biological Insights | Annales de Pathologie | 2026 | Review | Cancer Biology | Clinicopathologic and biological features of ILC; CDH1/E-cadherin loss; metastatic patterns; pathology diagnosis and immunohistochemistry; emerging therapeutic targets |
| Voorthuis | Invasive lobular breast cancer in young patients without adjuvant systemic treatment: 15-year survival outcomes | Breast Cancer Research and Treatment | 2026 | Lab Research | Incidence | Young patients; long-term survival; no adjuvant systemic treatment |
| Mazzoli | Effectiveness comparison of first-line CDK4/6 inhibitors in patients with hormone-positive HER2-negative advanced breast cancer according to tumor histology: a sub-analysis of the real-world, multicenter, Italian study PALMARES-2 | The Breast | 2026 | Review | Clinical Trials | histology, metastasis |
| Boysen | Radiation therapy for lobular breast cancer: opportunities and challenges for leveraging radiosensitivity | NPJ Breast Cancer | 2025 | Review | Treatment | ionizing radiation therapy (XRT) |
| Corso | Invasive lobular carcinoma: Strategies and perspectives from the lobular breast cancer research group | Elsevier | 2025 | Review | Treatment? | E-cadherin, endocrine therapy, neoadjuvant treatment |
| Diamond | Targeting DNA Repair Dysfunction in Lobular Breast Cancer by PARP Inhibition | Endocrinology | 2025 | Lab Research | Cell Signaling | cell biology |
| Foldi | Personalized Circulating Tumor DNA Testing for Detection of Progression and Treatment Response Monitoring in Patients With Metastatic Invasive Lobular Carcinoma of the Breast | JCO Precision Oncology | 2025 | Retrospective | Metastasis | ctDNA |
| Gupta | Invasive lobular carcinoma: integrated multi-omics analysis reveals silencing of Argininosuccinate synthase and upregulation of nucleotide biosynthesis in tamoxifen resistance | Cell Death & Disease | 2025 | Lab Research | Treatment? | Endocrine Resistance |
| Horvat | Comparison of Contrast-enhanced Mammography and Low-Energy Imaging with or without Supplemental Whole-Breast US in Breast Cancer Detection | Radiology | 2025 | Prospective | Imaging | contrast enhanced mammogram, ultrasound |
| Kaur | Socioeconomic status impacts tumor biology, treatment, and outcomes in over 200,000 patients with invasive lobular carcinoma of the breast: an analysis of the National Cancer Database | Springer Nature | 2025 | Retrospective | Epidemiology | Disparities, Prognosis |
| Kim | Node Reporting and Data System Evaluation of Axillary Nodes in Invasive Ductal and Lobular Carcinoma | Radiology | 2025 | Retrospective | Imaging | Node-RADS, lymph node, breast MRI |
| Knip | The Diagnostic Accuracy of 18F-FDG PET and 18F-FES PET for Staging Grade 1–2 Estrogen Receptor–Positive Breast Cancer | Radiology | 2025 | Prospective | Imaging | FES-PET, FDD-PET, ER+, staging |
| Middleton | Immediate and ipsilateral recurrence rates and treatment recommendations for patients with pleomorphic and florid lobular carcinoma in situ | Springer Nature | 2025 | Retrospective | Treatment? | PLCIS; FLCIS |
| Mouabbi | Immediate and ipsilateral recurrence rates and treatment recommendations for patients with pleomorphic and florid lobular carcinoma in situ | Breast Cancer Research and Treatment | 2025 | Retrospective | lobular carcinoma in situ, Clinicopathological, Prognosis | Recurrence rates |
| Mukhtar | Socioeconomic status impacts tumor biology, treatment, and outcomes in over 200,000 patients with invasive lobular carcinoma of the breast: an analysis of the National Cancer Database | Breast Cancer Research and Treatment | 2025 | Retrospective | Prognosis | Diagnosis, treatment, outcomes |
| Mukhtar | Accuracy of Breast MRI for Surgical Planning After Neoadjuvant Therapy for Patients with Invasive Lobular Carcinoma | Annals of Surgical Oncology | 2025 | Retrospective | Imaging | Breast MRI, Neoadjuvant Therapy |
| Mukhtar | Locoregional Considerations for Invasive Lobular Carcinoma | Springer Nature | 2025 | Review | Surgery | axillary management, neoadjuvant therapy |
| Musick | Genetic E-Cadherin Loss Creates a Distinct Phenotype in an Early ILC Tumorigenesis Model | Endocrinology | 2025 | Lab Research | Cancer Biology | e-cadherin |
| Raghavendra | Clinical Characteristics and Survival Outcomes of Metastatic Invasive Lobular and Ductal Carcinoma | JAMA | 2025 | Retrospective | Metastasis | clinicopathological, patterns |
| Rätze | Afadin loss induces breast cancer metastasis through destabilisation of E‐cadherin to F‐actin linkage | J Pathol | 2025 | Lab Research | Cancer Biology | e-cadherin |
| Rowland | Transcriptomic Analysis of MDC1 as a Novel Coregulator of Estrogen Receptor in ILC | Endocrinology | 2025 | Lab Research | Genomics | ER function in ILC |
| Ryu | Diagnostic Performance of 18F-Fluoroestradiol PET/CT for Axillary Lymph Node Metastasis in Invasive Lobular Carcinoma: A Prospective Feasibility Study | JNM | 2025 | Prospective | Imaging | FES PET/CT, metastasis, staging |
| Sandoval | Prognostic significance and predictive value of circulating tumor cells in invasive lobular breast carcinoma - an exploratory analysis of the STIC CTC trial | Clin Cancer Res | 2025 | Review | Clinical Trials | circulating tumor cells, metastatis |
| Sikora | Estrogen Receptor co-opts Mediator of DNA Damage Checkpoint 1 (MDC1) to Drive Epigenomic Remodeling and Transcriptional Regulation in ILC Cells | Endocrinology | 2025 | Lab Research | Cancer Biology | endocrine response and resistance |
| Singh Parihar | 18F-Fluorestradiol PET/CT for Predicting Benefit from Endocrine Therapy in Patients with Estrogen Receptor-Positive Breast Cancer: A Systemic Review and Metaanalysis | JNM | 2025 | Retrospective | Imaging | FES PET/CT, endocrine treatment |
| Vertido | Accuracy of Breast MRI for Surgical Planning After Neoadjuvant Therapy for Patients with Invasive Lobular Carcinoma | Ann Surg Oncol | 2025 | Retrospective | Imaging | MRI, neoadjuvant therapy |
| Zhang | Unique Molecular Alteration of Lobular Breast Cancer: Association with Pathological Classification, Tumor Biology and Behavior, and Clinical Management | Cancers | 2025 | Review | Clinicopathological | pathological classification, CDH1 gene, E-cadherin, tumor biomarkers, clinical managemen |
| Abigail | Glucocorticoid receptor-mediated oncogenic activity is dependent on breast cancer subtype | J Steroid Biochem Mol Biol | 2024 | Lab Research | Cancer Biology | Glucocorticoid Receptor |
| Alexander | Pathway-based signatures predict patient outcome, chemotherapy benefit and synthetic lethal dependencies in invasive lobular breast cancer | Br J Cancer | 2024 | Retrospective | Genomics | Prognostic Biomarkers |
| Alkhafaji | Circulating tumor cells in early lobular versus ductal breast cancer and their associations with prognosis | Npj Breast Cancer | 2024 | Retrospective | Prognosis | Liquid biopsies |
| Bahl | Impact of pre-operative MRI on surgical management of screening digital breast tomosynthesis-detected invasive lobular carcinoma | Breast Cancer Res Treat | 2024 | Retrospective | Imaging | MRI |
| Balatico | https://meridian.allenpress.com/aplm/article/148/3/263/499196/Male-Invasive-Lobular-Breast-Cancer | Arch Pathol Lab Med | 2024 | Retrospective | Clinicopathological | Male ILC |
| Batra | Exploration of cancer associated fibroblasts phenotypes in the tumor microenvironment of classical and pleomorphic Invasive Lobular Carcinoma | Front Oncol | 2024 | Lab Research | Cancer Biology | Tumor Microenvironment |
| Braunstein | Accelerated Partial Breast Irradiation for Early-Stage Invasive Lobular Carcinoma | Int J Radiat Oncol Biol Phys | 2024 | Retrospective | Radiation Oncology | Partial Breast Radiation |
| Cheng | Analysis of prognostic factors and construction of prognostic models for invasive lobular carcinoma of the breast | Biomol Biomed | 2024 | Risk Factors | Prognosis | Progostic Models |
| Coffey | Breast Radiologists’ Perceptions on the Detection and Management of Invasive Lobular Carcinoma: Most Agree Imaging Beyond Mammography Is Warranted | Journal of Breast Imaging | 2024 | Retrospective | Imaging | Imaging Methods |
| Coffey | Breast Radiologists’ Perceptions on the Detection and Management of Invasive Lobular Carcinoma: Most Agree Imaging Beyond Mammography Is Warranted | Journal of Breast Imaging | 2024 | Survey | Imaging | Breast Imaging |
| Corso | CDH1 Genotype Exploration in Women With Hereditary Lobular Breast Cancer Phenotype | JAMA Netw Open | 2024 | Prospective | Genomics | Hereditary CDH1 mutations |
| De Schepper | Integration of Pathological Criteria and Immunohistochemical Evaluation for Invasive Lobular Carcinoma Diagnosis: Recommendations From the European Lobular Breast Cancer Consortium | Modern Pathology | 2024 | Lab Research | Pathology | Diagnosis, ILC variants |
| Djerroudi | Molecular and Clinical Portrait of HER2-low Invasive Lobular Carcinomas | Mod Pathol | 2024 | Retrospective | Genomics | Her-2 low ILC |
| Djerroudi | https://www.modernpathology.org/article/S0893-3952(24)00150-9/fulltext | Mod pathol | 2024 | Retrospective | Clinicopatholgical | CDH1 Mutations |
| Dopeso | Genomic and epigenomic basis of breast invasive lobular carcinomas lacking CDH1 genetic alterations | npj Precis. Onc | 2024 | Lab Research | Genomics | CDH1 (lack of) |
| Falade | Variation in surgical treatment by body mass index in patients with invasive lobular carcinoma of the breast | Breast Cancer Res Treat | 2024 | Retrospective | Surgery | Body Mass Index |
| Falade | Oncologic Safety of Immediate Oncoplastic Surgery Compared with Standard Breast-Conserving Surgery for Patients with Invasive Lobular Carcinoma | Ann Surg Oncol | 2024 | Retrospective | Surgery | Oncoplastic Surgery |
| Flaherty | Is There a Special Role for Ovarian Hormones in the Pathogenesis of Lobular Carcinoma? | Endocrinology | 2024 | Review | Risk Factors | HRT |
| Foldi | Long-term outcomes by lobular vs ductal histology in 4 National Surgical Adjuvant Breast and Bowel Project adjuvant breast cancer trials | JNCI | 2024 | Retrospective | Clinicopathological | Prognosis |
| Geukens | Rapid autopsies to enhance metastatic research: the UPTIDER post-mortem tissue donation program | Npj Breast Cancer | 2024 | Retrospective | Metastasis | Rapid Autopsy |
| Giannoti | The role of contrast-enhanced mammography in the preoperative evaluation of invasive lobular carcinoma of the breast | Clin Radiol | 2024 | Retrospective | Imaging | Contrast Enhanced Mammography (CEM) |
| Gonzales-Martinez | CDH1 methylation analysis in invasive lobular breast carcinomas with and without gene mutation | Virchows Arch | 2024 | Lab Research | Genomics | CDh1 Mythelation |
| Gronewold | Microenvironment‐induced restoration of cohesive growth associated with focal activation of P‐cadherin expression in lobular breast carcinoma metastatic to the colon | J Pathol Clin Res | 2024 | Retrospective | Clinicopathological | Colon metastasis |
| Ilić | Differences in Histological Subtypes of Invasive Lobular Breast Carcinoma According to Immunohistochemical Molecular Classification | Diagnostics (Basel) | 2024 | Retrospective | Clinicopathological | Histological Subtypes of ILC |
| Izci | Adipocyte heterogeneity and tumor infiltration of adipose tissue in patients with metastatic breast cancer | Breast | 2024 | Retrospective | Metastasis | Tumor Infiltratiion |
| Katayama | Nuclear morphological characterisation of lobular carcinoma variants: a morphometric study | Hisotpathology | 2024 | Lab Research | Clinicopatholgical | Pleomorphic Variant |
| Kioleoglou | Gastrointestinal Metastases From Lobular Breast Carcinoma: A Literature Review | Cureus | 2024 | Review | Metastasis | GI Metastasis |
| Kolawole | The Alveolar Variant of Lobular Carcinoma and Its Mimickers: A Case Series | Cureus | 2024 | Case Studies | Clinicopathological | Alveolar Varient |
| Makhlouf | Deciphering the Clinical Behaviour of Invasive Lobular Carcinoma of the Breast Defines an Aggressive Subtype | Cancers | 2024 | Retrospective | Clinicopathological | ILC Variants |
| Mmed | Can 18F-FES PET Improve the Evaluation of 18F-FDG PET in Patients With Metastatic Invasive Lobular Carcinoma? | Clinical Nuclear Medicine | 2024 | Retrospective | Imaging | FES/FDG PET |
| Nakagawa | Potential role of Fbxo22 in resistance to endocrine therapy in breast cancer with invasive lobular carcinoma | Breast Cancer Res Treat | 2024 | Retrospective | Clinicopathological | Endocrine Resistance |
| Narayanan | Transcriptomic analysis identifies enrichment of cAMP/PKA/CREB signaling in invasive lobular breast cancer | Breast Cancer Res | 2024 | Lab Research | Cancer Biology | Cell signaling |
| O'Connor | Evaluating Surgical Outcomes Between Estrogen Receptor Positive Invasive Lobular and Invasive Ductal Carcinoma of the Breast-A Propensity Matched Analysis | Clin Breast Cancer | 2024 | Retrospective | Surgery | Prognosis |
| Oztekin | The effect of neoadjuvant chemotherapy on long-term survival outcomes in patients with invasive lobular breast cancer treated with endocrine therapy: A retrospective cohort study | Cancer | 2024 | Retrospective | Clinicopathological | Neo-Adjuvent Chemotherapy |
| Pabba | Stromal Tumor-Infiltrating Lymphocytes in Hormone Receptor-Positive/HER2 Negative Metastatic Breast Cancer | Mod Pathol | 2024 | Retrospective | Cancer Biology | Immune Landscape |
| Pareja | A Genomics-Driven Artificial Intelligence-Based Model Classifies Breast Invasive Lobular Carcinoma and Discovers CDH1 Inactivating Mechanisms | Cancer Res | 2024 | Lab Research | Genomics | Artificial Intelligence |
| Quirke | Invasive lobular carcinoma of the breast; clinicopathologic profile and response to neoadjuvant chemotherapy over a 15-year period | The Breast | 2024 | Retrospective | Clinicopathological | Neo-Adjuvent Chemotherapy |
| Rogges | Pleomorphic/solid lobular carcinoma of male breast with PALB2 germline mutation: case report and literature review - PMC | Pathologica | 2024 | Case Studies/Review | Clinicopathological | Male ILC |
| Shah | Spatial molecular profiling of mixed invasive ductal and lobular breast cancers reveals heterogeneity in intrinsic molecular subtypes, oncogenic signatures, and mutations | Proc Natl Acad Sci | 2024 | Clinicopathological | Cancer Biology | Tumor heterogeneity |
| Shin | Expression of PD-L1 in breast invasive lobular carcinoma | PLOs One | 2024 | Lab Research | Genomics | PDL-1 Expression; Immuno-oncology |
| Sikora | A Path to Precision Metabolic Treatment in Breast Cancer: Riluzole, Glutamate Signaling, and Invasive Lobular Carcinoma | Journal of the Endocrine Society | 2024 | Commentary | Cancer Biology | cell signaling |
| Sottnik | WNT4 Regulates Cellular Metabolism via Intracellular Activity at the Mitochondria in Breast and Gynecologic Cancers | Cancer Res Commun | 2024 | Lab Research | Cancer Biology | cell signaling |
| Uchida | Insights into E-Cadherin Impairment in CDH1-Unaltered Invasive Lobular Carcinoma: A Comprehensive Bioinformatic Study | Int J Mol Sci | 2024 | Clincopathological | Cancer Biology | CDH1 (non-mutated) |
| Ulaner | ER-Targeted PET for Initial Staging and Suspected Recurrence in ER-Positive Breast Cancer | AMA Netw Open | 2024 | Diagnostic study | Imaging | ER-Targeted PET |
| Ulaner | ER-Targeted PET for Initial Staging and Suspected Recurrence in ER-Positive Breast Cancer | JAMA Network | 2024 | Prospective | Clinical Trials | FES PET/CT, staging |
| Van Baalen | Reporting on invasive lobular breast cancer in clinical trials: a systematic review | Npj Breast Cancer | 2024 | Review | Clinicial Trials | Underreporting ILC, RECiST criteria |
| Van Hemert | Breast surgery after neoadjuvant chemotherapy in patients with lobular carcinoma: surgical and oncologic outcome | Breast Cancer Res Treat | 2024 | Retrospective | Surgery | Neo-Adjuvent Chemotherapy |
| Yates | ESR1 Fusions Invoke Breast Cancer Subtype-Dependent Enrichment of Ligand-Independent Oncogenic Signatures and Phenotypes | Endocrinology | 2024 | Lab Research | Clinicopathological | Estrogen Resistance |
| Zels | Metastases of primary mixed no-special type and lobular breast cancer display an exclusive lobular histology | The Breast | 2024 | Retrospective | Metastasis | Mixed NST/ILC |
| Zou | Systems approach for congruence and selection of cancer models towards precision medicine | PLoS Comput Biol | 2024 | Lab Research | Clinicopathological | Cell Models |
| Aliaga | Evolution of biological features of invasive lobular breast cancer: Comparison between primary tumour and metastases | EJC European Journal of Cancer | 2023 | Retrospective | Clinicopathological | Primary vs Metastatic Tumors |
| Amir | A role for breast ultrasound Artificial Intelligence decision support in the evaluation of small invasive lobular carcinomas | Clinical Imaging | 2023 | Retrospective | Imaging | Artificial Inteligence |
| Arce | Evaluation of an Artificial Intelligence System for Detection of Invasive Lobular Carcinoma on Digital Mammography | Cureus | 2023 | Retrospective | Imaging | Artificial Inteligence |
| Barakat | Achieving Intraperitoneal Disease Control Using Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy: Two Cases of Metastatic Breast Cancer | Cureus | 2023 | Case reports | Surgery | Peritoneal Metastatsis |
| Barbieri | A Rare Case of Duodenal Metastasis from Lobular Breast Cancer: From Diagnosis to Surgery | Case Report Oncology | 2023 | Case reports | Metastasis | Duodenal Metastasis |
| Batra | Lobular Carcinoma of the Breast: A Comprehensive Review with Translational Insights | Cancers | 2023 | Review | Clinicopathological | Characteristics of ILC |
| Bonnin | Performance of [18F]FDG-PET/CT Imaging in First Recurrence of Invasive Lobular Carcinoma | Journal of Clinical Medicine | 2023 | Retrospective | Imaging | FDG PET/CT |
| Bottoni | Diagnostic effectiveness of [18F]Fluoroestradiol PET/CT in oestrogen receptor-positive breast cancer: the key role of histopathology. Evidence from an international multicentre prospective study | Eur J Nucl Med Mol Imaging | 2023 | Prospective | Imaging | FES PET/CT |
| Clelland | Quantifying hormone receptor status in lobular breast cancer in an institutional series: the relationship between estrogen and progesterone receptor status and outcomes | Breast Canc Res Treat | 2023 | Retrospective | Clinocopathological | ER low + |
| Covington | Prospective Pilot Study of 18F-Fluoroestradiol PET/CT in Patients With Invasive Lobular Carcinomas | AJR | 2023 | Prospective | Imaging | FES PET/CT |
| Dayan | Effect of histological breast cancer subtypes invasive lobular versus non-special type on survival in early intermediate-to-high-risk breast carcinoma: results from the SUCCESS trials | Breast Cancer Research | 2023 | Retrospective | Prognosis | SUCCESS Trial |
| Eshet | The Role of 68Ga-FAPI PET/CT in Detection of Metastatic Lobular Breast Cancer | Clin Nucl Med | 2023 | Prospective | Imaging | FAPi Pet/CT |
| Fitzpatrick | Genomic profiling and pre-clinical modelling of breast cancer leptomeningeal metastasis reveals acquisition of a lobular-like phenotype | Nat Commun | 2023 | Lab Research | Genomics | Leptomeningeal Metastasis |
| Gilardi | FDG and Non-FDG Radiopharmaceuticals for PET Imaging in Invasive Lobular Breast Carcinoma | Biomedicines | 2023 | Review | Imaging | FDG, FES, FAPi |
| Giraldi | FDG and Non-FDG Radiopharmaceuticals for PET Imaging in Invasive Lobular Breast Carcinoma | Biomedicines | 2023 | Review | Imaging | PET Imaging |
| Goker | Tumor-Infiltrating Lymphocytes and PD-L1 Expression in Pleomorphic Lobular Breast Carcinoma | Cancers | 2023 | Retrospective | Clincopathologic/Genomics | Pleomorphic ILC |
| Göker | Histologic tumor type as a determinant of survival in hormone receptor-positive, HER2-negative, pT1-3 invasive ductal and lobular breast cancer | Breast Cancer Res | 2023 | Retrospective | Clinicopathological | Prognosis |
| Goldhaber | Is Choosing Wisely Wise for Lobular Carcinoma in Patients Over 70 Years of Age? A National Cancer Database Analysis of Sentinel Node Practice Patterns | Ann Surg Oncol | 2023 | Retrospective | Surgery | Sentinal node biopsy |
| Jochelson | Editorial: Contrast mammography-a promising tool for the pre-operative evaluation of lobular breast cancer | European Journal of Radiology | 2023 | editorial | imaging | contrast enhanced mammogram |
| Kaur | Area Deprivation Index in patients with invasive lobular carcinoma of the breast: associations with tumor characteristics and outcomes | Cancer Epidemiol Biomarkers | 2023 | Retrospective | Epidemiology | Tumor Characteristics and outcomes |
| Kawaguchi | High-accuracy prediction of axillary lymph node metastasis in invasive lobular carcinoma using focal cortical thickening on magnetic resonance imaging | Breast Cancer | 2023 | Retrospective | Imaging | MRI |
| Li | A study of clinical and molecular characteristics in bilateral primary breast cancer | Cancer Med | 2023 | Retrospective | Cllnicopathological | Bilateral Breast Cancer |
| Lobbes | The performance of contrast-enhanced mammography and breast MRI in local preoperative staging of invasive lobular breast cancer | Eur J Radiol | 2023 | Retrospective | Imaging | CEM/MRI |
| Mankoff | Summary: SNMMI Procedure Standard/EANM Practice Guideline for Estrogen Receptor Imaging of Patients with Breast Cancer Using 16α-[18F]Fluoro-17β-Estradiol PET | JNM | 2023 | summary | imaging | estrogen receptor imaging, practice guidelines, [F18]FES PET |
| Morrison | Bone Marrow Only Metastases from Lobular Carcinoma: Insights into Responses to Endocrine
Therapy | Ann Oncol Case Rep | 2023 | Case Studies | Metastasis | Bone Marrow Metastasis |
| Mouabbi | Absence of lobular carcinoma in situ is a poor prognostic marker in invasive lobular carcinoma | EJC European Journal of Cancer | 2023 | Retrospective | Prognosis | LCIS |
| Muradali | Preoperative Breast Magnetic Resonance Imaging: An Ontario Health (Cancer Care Ontario) Clinical Practice Guideline | Curr Oncol | 2023 | Review | Imaging | MRI |
| Nasrazadani | Mixed invasive ductal lobular carcinoma is clinically and pathologically more similar to invasive lobular than ductal carcinoma | Br J Cance | 2023 | Retrospective | Clinicopathological | Mixed ILC/IDC |
| Olukoya | Riluzole Suppresses Growth and Enhances Response to Endocrine Therapy in ER+ Breast Cancer | J Endocr Soc | 2023 | Lab Research | Cancer Biology | cell signaling |
| Onega | Digital mammography and digital breast tomosynthesis for detecting invasive lobular and ductal carcinoma | Breast Cancer Res Treat | 2023 | Retrospective | Imaging | Digital Mammography/Tomsynthsis |
| Onkar | Immune landscape in invasive ductal and lobular breast cancer reveals a divergent macrophage-driven microenvironment | Nat Cancer | 2023 | Lab Research | Genomics | Immunology |
| Pereslucha | Invasive Lobular Carcinoma: A Review of Imaging Modalities with Special Focus on Pathology Concordance | Healthcare | 2023 | Review | Imaging | MRI vs CEM |
| Porter | Glucocorticoid Receptor Activation in Lobular Breast Cancer Is Associated with Reduced Cell Proliferation and Promotion of Metastases | Cancers | 2023 | Lab Research | Cancer Biology | Tumor Microenvironment |
| Ramalingam | Successful Breast Conservation After Neoadjuvant Chemotherapy in Lobular Breast Cancer: The Role of Menopausal Status in Response to Treatment | Ann Surg Oncol | 2023 | Retrospective | Surgery | Menopausal Status |
| Record | Tamoxifen or aromatase inhibitors with ovarian function suppression in pre-menopausal stage I-III lobular breast cancer | Npj Breast Cancer | 2023 | Retrospective | Clinicalpathological | Adjuvent Therapy |
| Ribinkar | Association between PIK3CA activating mutations and outcomes in early-stage invasive lobular breast carcinoma treated with adjuvant systemic therapy | Radiol Oncol | 2023 | Retrospective | Genomics | Pik3CA mutations |
| Rothschild | Predictors of Early Versus Late Recurrence in Invasive Lobular Carcinoma of the Breast: Impact of Local and Systemic Therapy | Ann Surg Oncol | 2023 | Retrospective | Clinicopathological | Local Recurrances |
| Rothschild | HER-2 low status in early-stage invasive lobular carcinoma of the breast: associated factors and outcomes in an institutional series | Breast Cancer Res Treat | 2023 | Retrospective | Clinicopathological | Her2 low |
| Rothschild | The impact of histologic subtype on primary site surgery in the management of metastatic lobular versus ductal breast cancer: a population based study from the National Cancer Database | Epidemiology | 2023 | - | surgery | metastasis, overall survival |
| Sflomos | Optimized Modeling of Metastatic Triple-Negative Invasive Lobular Breast Carcinoma | Cancers | 2023 | Lab Research | ILC Models | TNBC-ILC |
| Sijnesael | Canonical Kaiso target genes define a functional signature that associates with breast cancer survival and the invasive lobular carcinoma histological type | Journal of Pathology | 2023 | - | cancer genetics | e-cadherin, gene signature, KART, Kaiso, ER positive HER2 negative |
| Thill | Treatment and outcome in metastatic lobular breast cancer in the prospective German research platform OPAL | Breast Cancer Res Treat | 2023 | Prospective | Clinicopathological | Prognosis |
| Thomas | Rare subtypes of triple negative breast cancer: Current understanding and future directions | NPJ Breast Cancer | 2023 | Retrospective | Clinicopathological | TNBC Subtypes |
| Trillo | Evolution of biological features of invasive lobular breast cancer: Comparison between primary tumour and metastases | Eur J Cancer | 2023 | Retrospective | Cancer Biology | Primary vs metastatic ILC |
| Van Baelen | Association of body mass index with clinicopathological features and survival in patients with primary invasive lobular breast cancer | EJC European Journal of Cancer | 2023 | Retrospective | Prognosis | Body mass Index |
| Voorwerk | PD-L1 blockade in combination with carboplatin as immune induction in metastatic lobular breast cancer: the GELATO trial. . | Nat Cancer | 2023 | Prospective | Clinicopathological | Immunotherapy |
| Wang | Construction of immune score and its prognostic value in invasive lobular carcinoma of the breast using computational pathology analysis | Cancer Medicine | 2023 | Retrospective | Cancer Biology | Immune cells |
| Yu | Clinicopathologic and genomic features of lobular like invasive mammary carcinoma: is it a distinct entity? | NPJ Breast Cancer | 2023 | Retrospective | Clincopathologic/Genomics | Lobular Like IDC's (LMMCA) |
| Abel | The 21-Gene Recurrence Score in Clinically High-Risk Lobular and Ductal Breast Cancer: A National Cancer Database Study | Ann Surg Oncology | 2022 | Retrospective | Clinicopathological | Prognostic Biomarkers |
| Alexander | Assessment of the Molecular Heterogeneity of E-Cadherin Expression in Invasive Lobular Breast Cancer | Cancers (Basel) | 2022 | Clinicopathological | Genomics | E-Cadherin |
| Allen | VIVA1: a more invasive subclone of MDA-MB-134VI invasive lobular carcinoma cells with increased metastatic potential in xenograft models | British Journal of Cancer | 2022 | Lab Research | Cancer Biology | ILC Models |
| Bahnassy | Unlocking the Mysteries of Lobular Breast Cancer Biology Needs the Right Combination of Preclinical Models | Mol Cancer Res | 2022 | Review | Cancer Biology | ILC Models |
| Bhaludin | A review on the added value of whole-body MRI in metastatic lobular breast cancer | Eur Radiol | 2022 | Review | Imaging | MRI |
| Bodopati | 18F-FES PET/CT Improves the Detection of Intraorbital Metastases in Estrogen-Receptor-Positive Breast Cancer: Two Representative Cases and Review of the Literature | Tomography | 2022 | Case Reports | Imaging | Orbital metastases |
| Busbait | Occult Invasive Lobular Carcinoma: Presenting as an Axillary Skin Metastatic Lesion Underwent Neoadjuvant Endocrine Therapy and Surgical Resection | Breast Cancer | 2022 | Case Study | Metastasis | Skin Metastasis |
| Christgen | Inter-observer agreement for the histological diagnosis of invasive lobular breast carcinoma | J Pathol Clin Res | 2022 | Lab Research | Clinicopathological | Diagnosis |
| Constantini | Diagnostic Challenge of Invasive Lobular Carcinoma of the Breast: What Is the News? Breast Magnetic Resonance Imaging and Emerging Role of Contrast-Enhanced Spectral Mammography | J Pers med | 2022 | Retrospective | Imaging | MRI/CESM |
| Davis | Circulating tumour DNA characterisation of invasive lobular carcinoma in patients with metastatic breast cancer | E Bio Medicine | 2022 | Retrospective | Metastasis | Genomics, ctDNA |
| de Gregorio | The impact of anthracyclines in intermediate and high-risk HER2-negative early breast cancer—a pooled analysis of the randomised clinical trials PlanB and SUCCESS C | Br J Cancer | 2022 | Review | Clinicopathological | Chemotherapy |
| De Schepper | Results of a worldwide survey on the currently used histopathological diagnostic criteria for invasive lobular breast cancer | Mod Pathology | 2022 | Guidelines | Clinicopathological | Diagnosis |
| Djerroudi | Invasive Lobular Carcinoma of the Breast: Toward Tailoring Therapy? | JNCI | 2022 | Editorial | Clinicopathological | Prognosis |
| Dołęga-Kozierowski | Multimodality imaging in lobular breast cancer: Differences in mammography, ultrasound, and MRI in the assessment of local tumor extent and correlation with molecular characteristics | Front Oncol | 2022 | Retrospective | Imaging | Imaging Modalities/Breast |
| Elangovan | Loss of E-cadherin Induces IGF1R Activation and Reveals a Targetable Pathway in Invasive Lobular Breast Carcinoma | Mol Cancer Res | 2022 | Lab Research | Cancer Biology | E-cadherin and cell signaling |
| Fimereli | Timing evolution of lobular breast cancer through phylogenetic analysis | EBioMedicine | 2022 | Retrospective | Genomics | Metastasis |
| Fitzpatrick | Assessing CSF ctDNA to improve diagnostic accuracy and therapeutic monitoring in breast cancer leptomeningeal metastasis | Clin Canc Research | 2022 | Retrospective | Genomics | Leptomingeal metastasis |
| Gomez-Cuadrado | Characterisation of the Stromal Microenvironment in Lobular Breast Cancer | Cancers | 2022 | Lab Research | Cancer Bioligy | Tumor Microenvironment |
| Grote | ERBB2 mutation is associated with sustained tumor cell proliferation after short-term preoperative endocrine therapy in early lobular breast cancer | Modern Pathology | 2022 | Retrospective | Genomics | ERBB2 mutations |
| Lee | Chromatin accessibility landscape and active transcription factors in primary human invasive lobular and ductal breast carcinomas | Breast Cancer Research | 2022 | Lab Research | Genomics | Epigenomics |
| LeNoue-Newton | Natural History and Characteristics of ERBB2-mutated Hormone Receptor–positive Metastatic Breast Cancer: A Multi-institutional Retrospective Case–control Study from AACR Project GENIE | Clin Canc Research | 2022 | Retrospective | Genomics | ERBB2 mutations |
| Makower | The 21-gene recurrence score in early non-ductal breast cancer: a National Cancer Database analysis | NPJ Breast | 2022 | Retrospective | Clinicopathological | Prognostic Biomarkers |
| Mouabbi | Histology-based survival outcomes in hormone receptor-positive metastatic breast cancer treated with targeted therapies | NPJ Breast Cancer | 2022 | Retrospective | Clinicopatholical | Targeted therapy in ILC vs. IDC |
| Mouabbi | Invasive lobular carcinoma: an understudied emergent subtype of breast cancer | Breast Cancer Res Treat | 2022 | Review | Clinicopathological | Characteristics of ILC |
| Nardone | A Distinct Chromatin State Drives Therapeutic Resistance in Invasive Lobular Breast Cancer | Cancer Res | 2022 | Lab Research | Cancer Biology | Epigenomics |
| O'Connor | Differences in sensitivity to neoadjuvant chemotherapy among invasive lobular and ductal carcinoma of the breast and implications on surgery–A systematic review and meta-analysis | Breast | 2022 | Review | Surgery | Neoadjuvent chemotherapy |
| Oesterreich | Clinicopathological Features and Outcomes Comparing Patients With Invasive Ductal and Lobular Breast Cancer | JNCI | 2022 | Retrospective | Clinicopathological | Prognosis |
| Okines | Clinical outcomes in patients with triple negative or HER2 positive lobular breast cancer: a single institution experience | Breast Cancer Res Treat | 2022 | Retrospective | Clinicopathological | TNBC, Her2 ILC |
| Ratze | Loss of E-cadherin leads to Id2-dependent inhibition of cell cycle progression in metastatic lobular breast cancer | Oncogene | 2022 | Lab Research | Cancer Biology | E-Cadherin |
| Sun | De novo metastatic lobular breast carcinoma: A population-based study from SEER database | Asian J Surg | 2022 | Retrospective | Metastasis | Prognosis |
| Tsutsui | Orbital metastasis of invasive lobular carcinoma of the breast | J Surg Case Rep. | 2022 | Case Study | Metastasis | Orbital Metastasis |
| Van Baelen | Current and future diagnostic and treatment strategies for patients with invasive lobular breast cancer | Annals of Oncology | 2022 | Review | Clinicopathological | Treatment Strategies |
| Weiser | Adjuvant chemotherapy in patients with invasive lobular carcinoma and use of the 21-gene recurrence score: A National Cancer Database analysis | Cancer | 2022 | Retrospective | Clinicopathological | Adjuvent Chemotherapy |
| Zhang | Biomarker profile of invasive lobular carcinoma: pleomorphic versus classic subtypes, clinicopathological characteristics and prognosis | Breast Cancer Res Treat | 2022 | Retrospective | Clinicopathological | Pleomorphic ILC |
| Abel | Decreased enrollment in breast cancer trials by histologic subtype: does invasive lobular carcinoma resist RECIST? | NPJ Breast Cancer | 2021 | Retrospective | Clinical Trials | RECIST criteria |
| Bergeron | Triple-negative breast lobular carcinoma: a luminal androgen receptor carcinoma with specific ESRRA mutations | Nature | 2021 | Retrospective | Genomics | Triple-negative ILC |
| Chamalidou | Survival patterns of invasive lobular and invasive ductal breast cancer in a large population-based cohort with two decades of follow up | The Breast | 2021 | Retrospective | Clinicopathological | Prognosis |
| Chen | Single-Cell Transcriptomic Heterogeneity in Invasive Ductal and Lobular Breast Cancer Cells | Cancer Res | 2021 | Lab Research | Cancer Biology | Genomics |
| Christgen | Lobular Breast Cancer: Histomorphology and Different Concepts of a Special Spectrum of Tumors | Cancers | 2021 | Review | ILC Variants | Tumor characteristics, variants, microenvironment |
| Cocco | Invasive Lobular Breast Cancer: Data to Support Surgical Decision Making | Ann Surg Onc | 2021 | Retrospective | Surgery | MRI |
| Conforti | Biological and clinical features of triple negative Invasive Lobular Carcinomas of the breast. Clinical outcome and actionable molecular alterations | Breast | 2021 | Retrospective | Clinicopathological | TNBC |
| Gamble | Association Between Hereditary Lobular Breast Cancer Due to CDH1 Variants and Gastric Cancer Risk | Jama Surgery | 2021 | Prospective | Hereditary Risk | Germline CDH1 Mutation |
| Gao | Peritoneal Metastasis After Treated With Abemaciclib Plus Fulvestrant for Metastatic Invasive Lobular Breast Cancer: A Case Report and Review of the Literature | Frontiers in Endocrinology | 2021 | Case Report | Metastasis | Peritoneal Metastasis |
| He | HER2 Positive and HER2 Negative Classical Type Invasive Lobular Carcinomas: Comparison of Clinicopathologic Features | Curr Oncology | 2021 | Retrospective | Clinicopathological | Her2+ ILC |
| Hovis | Accuracy of Preoperative Breast MRI versus Conventional Imaging in Measuring Pathologic Extent of Invasive Lobular Carcinoma | Journal of Breast Imaging | 2021 | Retrospective | Imaging | MRI |
| Jenkins | The 70-gene signature test as a prognostic and predictive biomarker in patients with invasivelobular breast cancer | Breast Cancer Res Treat | 2021 | Retrospective | Genomics | Gene Signatures |
| McCart Reed | The Genomic Landscape of Lobular Breast Cancer | Cancers (Basel) | 2021 | Retrospective | Genomics | Prognosis |
McCart
Reed | Invasive lobular
carcinoma of the breast: the increasing importance of this special subtype | Breast Cancer Res | 2021 | Review | Cancer Biology | Genomics and Pathology of ILC |
| Mills | Increased Risk for Ipsilateral Breast Tumor Recurrence in Invasive Lobular Carcinoma after Accelerated Partial Breast Irradiation Brachytherapy | The Oncologist | 2021 | Retrospective | Radiology | Radiation |
| Mohamed | The
overexpression of DNA repair genes in invasive ductal and lobular breast
carcinomas: Insights on individual variations and precision medicine | PLOS One | 2021 | Retrospective | Genomics | DNA damage response |
| Mukhtar | Changes
in Management Strategy and Impact of Neoadjuvant Therapy on Extent of Surgery
in Invasive Lobular Carcinoma of the Breast: Analysis of the National Cancer
Database (NCDB) | Annals of Surg Onc | 2021 | Retrospective | Surgery | Neoadjuvent Therapy Response |
| Mukhtar | Invasive
Lobular Carcinoma of the Breast: Ongoing Trials, Challenges, and Future
Directions | Clinical Trials | 2021 | Review | Clinicopathological | Clinical Trials |
| Naresh | An unwelcome guest: two cases of colonic metastatic lobular breast cancer | J Surg Case Rep | 2021 | Case reports | Metastasis | Colonic Metastases |
| Nunes | Prognostic Utility of Breast Cancer Index to Stratify Distant Recurrence Risk in Invasive Lobular Carcinoma | Clin Cancer Res | 2021 | Retrospective | Prognosis | Prognostic Biomarkers |
| Pate | How Researchers, Clinicians and Patient Advocates Can Accelerate Lobular Breast Cancer Research | Cancers | 2021 | Review | Research | Advocacy |
| Pramod | Comprehensive
review of molecular mechanisms and clinical features of invasive lobular
cancer | The Oncologist | 2021 | Review | Clinicopathological | Molecular and clinical features
of ILC |
| Reed | Invasive lobular carcinoma of the breast: the increasing importance of this special subtype | BMC Cancer | 2021 | Review | Pathology | Histopathology, microenvironment, clinical trials |
| Riedlinger | Targetable alterations in invasive pleomorphic lobular carcinoma of the breast | Breast Cancer Res | 2021 | Retrospective | Genomics | Pleomorphic ILC |
| Romanucci | Lobular Breast Cancer Conspicuity on Digital BreastTomosynthesis Compared to Synthesized 2D Mammography: A Multireader Study | J Imaging | 2021 | Retrospective | Imaging | Imaging Modalities |
| Rothschild | Obesity and menopausal status impact the features and molecular phenotype of invasive lobular breast cancer | Breast Cancer Res Treat | 2021 | Retrospective | Risk Factors | BMI |
| Sflomos | Atlas of Lobular Breast Cancer Models: Challenges and Strategic Directions | Cancers | 2021 | Review | Cancer Biology | ILC Models |
| Sflomos | Intraductal
xenografts show lobular carcinoma cells rely on their own extracellular
matrix and LOXL1 | Embo Molecular Med | 2021 | Lab Research | Cancer biology | Tumor microenvironment |
| Sottnick | Mediator of DNA damage
checkpoint 1 (MDC1) is a novel estrogen receptor co-regulator in invasive
lobular carcinoma of the breast | Mol Cancer Res | 2021 | Lab Research | Cancer Biology | Estrogen Receptor |
| Suman | Association of
variably methylated tumour DNA regions with overall survival for invasive
lobular breast cancer | Clin Epigenetics | 2021 | Retrospective | Genomics | Epigenomics |
| Timbres | Survival Outcomes in Invasive Lobular Carcinoma Compared to Oestrogen Receptor-Positive Invasive Ductal Carcinoma. Cancers | Cancers (Basel) | 2021 | Retrospective | Clinicopathological | Prognosis |
| Trapani | Benefit
of Adjuvant Chemotherapy in Patients with Lobular Breast Cancer: a Systematic
Review of the Literature and Metanalysis | Cancer Treatment Review | 2021 | Review | Clinicopathological | Therapy Response |
Van der
Veen | Extended
gene panel testing in lobular breast cancer | Familial Cancer | 2021 | Retrospective | Hereditary Breast Cancer | Germline (Herditary) Mutations |
| van Maaren | Trends in incidence, treatment, survival and subsequent breast cancer in lobular carcinoma in situ in the Netherlands: A population-based analysis | The Breast | 2021 | Retrospective | Incidence | LCIS |
| Wilson | Lobular Breast Cancer-A Review | Frontiers in Oncology | 2021 | Review | Clinicopathological | Molecular and Clinical features of ILC |
| Wong | Infiltrative pattern of metastatic invasive lobular breast carcinoma in the abdomen: a pictorial review | Insights Imaging | 2021 | Review | Imaging | Abdominal Metastasis |
| Yadav | Germline Pathogenic Variants in Cancer Predisposition Genes Among Women With Invasive Lobular Carcinoma of the Breast | J Clin onc | 2021 | Retrospective | Hereditary Risk | Germline Mutations |
| Yasui | Expression of N-Terminal-Deficient E-Cadherin Protein in Invasive Lobular Carcinoma of the Breast | Am J Surg pathol | 2021 | Lab Research | Tumor Biomarkers | E-Cadherin |
| Abdallah | Metastatic Breast Lobular Carcinoma to Unusual Sites: A Report of Three Cases and Review of Literatures | J Med Cases | 2020 | Case Report | Metastasis | GI metastases |
| Abel | Breast conservation therapy versus mastectomy in the surgical management of invasive lobular carcinoma measuring 4 cm or greater | Amer J of Surgery | 2020 | Retrospective | Surgery | Prognosis |
| Bergeron | An exceptional metaplastic lobular breast carcinoma diagnosed through exome sequencing. | J Clin Path | 2020 | Case Report | Genomics | Metaplastic Carcinoma |
| Blohmer | Patient treatment and outcome after breast cancer orbital and periorbital metastases: a comprehensive case series including analysis of lobular versus ductal tumor histology | Breast Cancer Res | 2020 | Retrospective | Metastasis | Oribital Metastasis |
| Carbognin | Targeted next-generation sequencing identifies genomic abnormalities potentially driving the prognosis of early-stage invasive lobular breast carcinoma patients stratified according to a validated clinico-pathological model.Targeted next-generation sequencing identifies genomic abnormalities potentially driving the prognosis of early-stage invasive lobular breast carcinoma patients stratified according to a validated clinico-pathological model | Breast | 2020 | Lab Research | Genomics | Prognosis |
| Christgen | Differential impact of prognostic parameters in hormone receptor-positive lobular breast
cancer | Cancer | 2020 | Retrospective | Clinicopathological | Prognostic Biomarkers |
| Findlay-Shirras | Population Trends in Lobular Carcinoma of the Breast: The Ontario Experience | Ann Surg Oncol | 2020 | Retrospective | Clinicopathological | Prognosis |
| Grabenstetter | E-cadherin
immunohistochemical expression in invasive lobular carcinoma of the breast:
correlation with morphology and CDH1 somatic alterationsE-cadherin immunohistochemical expression in invasive lobular carcinoma of the breast: correlation with morphology and CDH1 somatic alterations | Human Pathology | 2020 | Retrospective | Clinicopathological | e-Cadherin/CDH1 |
| Hu | Adjuvant chemotherapy could not bring survival benefit to HR-positive, HER2-negative, pT1b-c/N0–1/M0 invasive lobular carcinoma of the breast: a propensity score matching study based on SEER database | BMC Cancer | 2020 | Retrospective | Clinicopathological | Chemotherapy |
| Karjol | Bladder
Metastasis from Breast Cancer: A Systematic Review | Cereus | 2020 | Review | Clinicopathological | Bladder Metastasis |
| Kee | Human epidermal growth factor receptor 2 positive rates in invasive lobular breast carcinoma: The Singapore experience | World J Clin Oncol | 2020 | Retrospective | Clinicopathological | HER2+ ILC |
| Klarenbeek | Response of
metastatic mouse invasive lobular carcinoma to mTOR inhibition is partly
mediated by the adaptive immune system | Oncoimmunology | 2020 | Lab Research | Cancer Biology | mTor Inhibition |
| Kurozumi | Targetable ERBB2
mutation status is an independent marker of adverse prognosis in estrogen
receptor positive, ERBB2 non-amplified primary lobular breast carcinoma: a
retrospective in silico analysis of public datasets | Breast Cancer Research | 2020 | Retrospective | Cancer Biology | ERBB2/Her2 mutations |
| Laenkholm | Population-based Study of
Prosigna-PAM50 and Outcome Among Postmenopausal Women With Estrogen
Receptor-positive and HER2-negative Operable Invasive Lobular or Ductal
Breast Cancer. | Clin Breast Cancer | 2020 | Retrospective | Genomics | Prognostic Biomarkers |
| Montanagh | Invasive lobular
carcinoma with papillary features: A newly described variant that poses a
difficult histologic differential diagnosis. | Breast J | 2020 | Case Report | Clinicopathologal | Papillary Carcinoma |
| Mukhtar | Mitotic Score and
Pleomorphic Histology in Invasive Lobular Carcinoma of the Breast: Impact on
Disease-Free Survival | Breast Cancer Res Treat | 2020 | Retrospective | Clinicopathological | Pleomorphic ILC |
| Narbe | The Distribution of
Circulating Tumor Cells Is Different in Metastatic Lobular Compared to Ductal
Carcinoma of the Breast-Long-Term Prognostic Significance | Cells | 2020 | Retrospective | Metastasis | Circulating Tumor Cells |
| Orlandi | Palbociclib Plus Fulvestrant or Everolimus Plus Exemestane for Pretreated Advanced Breast Cancer with Lobular Histotype in ER+/HER2− Patients: A Propensity Score-Matched Analysis of a Multicenter Retrospective Patient Series | J Pers med | 2020 | Retrospective | Clinicopathological | Metastatic ILC |
| Pareja | The genomic landscape of metastatic histologic special types of invasive breast cancer | npj breast cancer | 2020 | Retrospective | Genomic | Mutations in Metastatic ILC |
| Richard | Characterization of Stromal Tumor-infiltrating Lymphocytes and Genomic Alterations in Metastatic Lobular Breast Cancer | Clin Cancer Research | 2020 | Lab Research | Genomics | Mutations in metastatic ILC |
| Schipper | Truncated
ASPP2 Drives Initiation and Progression of Invasive Lobular Carcinoma via
Distinct Mechanisms | Cancer Res | 2020 | Lab Research | Cancer Biology | Lab Models |
| Sestak | Prognostic
Value of EndoPredict in Women with Hormone Receptor-Positive, HER2-Negative
Invasive Lobular Breast Cancer | Clin Cancer Res | 2020 | Retrospective | Prognosis | Prognostic Biomarkers |
| Shackleford | Estrogen
Regulation of mTOR Signaling and Mitochondrial Function in Invasive Lobular
Carcinoma Cell Lines Requires WNT4 | Cancers | 2020 | Lab Research | Cancer biology | Estrogen signaling |
| Shamir | Genetic analysis of
pleomorphic and florid lobular carcinoma in situ variants: frequent
ERBB2/ERBB3 alterations and clonal relationship to classic lobular carcinoma
in situ and invasivelobular carcinoma | Mod Pathol | 2020 | Retrospective | Genomics | ERBB2/3(Her2) mutation in
Pleomorphic and Florid LCIS/ILC |
| Son | Oncological
Outcomes of Total Skin-Sparing Mastectomy for Invasive Lobular Carcinoma of
the Breast: A 20-Year Institutional Experience | Ann Surg Onc | 2020 | Retrospective | Surgery | Surgical Methods |
| Sreekumar | Differential
regulation and targeting of estrogen receptor α turnover in invasive
lobular breast carcinoma | Endocrinology | 2020 | Lab Research | Cancer Biology | Endocrine Response (SERDS) |
| Tille | Tumor-infiltrating
lymphocytes are associated with poor prognosis in invasive lobular breast
carcinoma | Mod Pathol | 2020 | Retrospective | Cancer Biology | Immunology |
| Ulaner | Head-to-head evaluation of
18F-FES and 18F-FDG PET/CT in metastatic invasive lobular breast cancer | J Nu Med | 2020 | Review | Imaging | FES PET/CT |
| Watanuki | Impact of neoadjuvant and
adjuvant chemotherapy on invasive lobular carcinoma: A propensity
score-matched analysis of SEER data | Breast J | 2020 | Retrospective | Clinicopathological | Chemotherapy |
| Westhoff | Prognostic relevance of the loss of stromal CD34 positive fibroblasts in invasive lobular carcinoma of the breast | Virchous Archiv | 2020 | Retrospective | Clinicopathological | Tumor Microenvironment |
| Yang | Comparison of
Overall Survival Between Invasive Lobular Breast Carcinoma and Invasive
Ductal Breast Carcinoma: A Propensity Score Matching Study Based on SEER
Database | Frontiers in Cancer | 2020 | Retrospective | Clinicopathological | Prognosis |
| Cao | Frequent amplifications of ESR1, ERBB2 and MDM4 in primary invasive lobular breast carcinoma | Cancer Letter | 2019 | Lab Research | Cancer biology | Genomics |
| Conforti | Endocrine-responsive lobular carcinoma of the breast: features associated with risk of late distant recurrence | Breast Cancer Res | 2019 | Retrospective | Risk Factors | Late Recurrence/Metastasis |
| Corona | Management of the axilla in breast cancer: outcome analysis in a series of ductal versus lobular invasive cancers | Breast Cancer Res Treat | 2019 | Retrospective | Surgery | Lymph node metastasis |
| Crown | Intraoperative radiation therapy in early-stage breast cancer: Presence of lobular features is not associated with increased rate of requiring additional therapy. | Am J Surg | 2019 | Retrospective | Surgery | Intra-operative Radiation |
| Dania | Associations of race and ethnicity with risk of developing invasive breast cancer after lobular carcinoma in situ | Breast Cancer Res | 2019 | Retrospective | Risk Factors | Race/Ethnicity |
| Davis | Association of a novel circulating tumor DNA next-generating sequencing platform with circulating tumor cells (CTCs) and CTC clusters in metastatic breast cancer | Breast Cancer Research | 2019 | Prospective | Metastasis | Liquid biopsies |
| de Nonneville | Adjuvant Chemotherapy in Lobular Carcinoma of the Breast: A Clinicopathological Score Identifies High-Risk Patient With Survival Benefit | Breast Cancer Res | 2019 | Retrospective | Clinicopathological | Chemotherapy |
| Desmedt | ESR1 mutations in metastatic lobular breast cancer patients | npj Breast Cancer | 2019 | Retrospective | Genomics | ESR1 Mutation |
| Dessauvagie | Invasive lobular carcinoma of the breast: assessment of proliferative activity using automated Ki-67 immunostaining | Pathology | 2019 | Retrospective | Clinicopathological | Ki67 |
| DiPiro | Lobular breast cancer: patterns of intraabdominal metastatic spread on imaging and prognosticsignificance | Abdom Radiology | 2019 | Retrospective | Metastasis | Abdominal Metastasis |
| Flores-Diaz | Impact of invasive lobular carcinoma on long-term outcomes in Mexican breast cancer patients | Breast Cancer Res Treat | 2019 | Retrospective | Clinicopathological | Prognosis |
| Franzoi | Leptomeningeal
carcinomatosis in patients with breast cancer. | Crit Rev Oncol Hematol | 2019 | Review | Metastasis | Leptomeningal Metastasis |
| Gao | CDK4/6 inhibitor treatment for patients with hormone receptor-positive, HER2-negative, advanced or metastatic breast cancer | Lancet Oncol | 2019 | Retrospective | Clinicopathological | CDK4/6 inhibitor response |
| Harrison | Genomic profiling of
pleomorphic and florid lobular carcinoma in situ reveals highly recurrent
ERBB2 and ERRB3 alterations | Mod Pathol | 2019 | Retrospective | Genomics | ERBB2 ,ERBB3/(Her2) Mutations |
| Kutasovic | Breast cancer
metastasis to gynaecological organs: a clinicoâ€pathological and
molecular profiling study | J Pathol Clin Res | 2019 | Retrospective | Genomics | Gynocological Metastasis |
| Levine | FGFR4
overexpression and hotspot mutations in metastatic ER+ breast cancer are
enriched in the lobular subtype | NPJ Breast Cancer | 2019 | Lab Research | Genomics | Metastasis |
| Luveta | Invasive
Lobular Breast Cancer as a Distinct Disease: Implications for Therapeutic
Strategy | Oncol and Therapy | 2019 | Review | Cancer Biology | Genomics and Therapeutic strategies |
| Mamtani | Lobular
Histology Does Not Predict the Need for Axillary Dissection Among ACOSOG
Z0011-Eligible Breast Cancer | Ann Surg Oncol | 2019 | Retrospective | Surgery | Lymph Node Dissection |
McCart
Reed | LobSig is a
multigene predictor of outcome in invasive lobular carcinoma | NPJ Breast Cancer | 2019 | Lab Research | Genomics | Gene signatures |
| Petridis | Frequency of Pathogenic
Germline Variants in CDH1, BRCA2, CHEK2, PALB2, BRCA1, and TP53 in Sporadic
Lobular Breast Cancer | Cancer Epidemiol Biomark | 2019 | Retrospective | Genomics | Genetic basis of ILC |
| Rosa-Rosa | High Frequency
of ERBB2 Activating Mutations in Invasive Lobular Breast Carcinoma with
Pleomorphic Features | Cancers | 2019 | Retrospective | Cancer biology | Her2(ERBB2) mutation in PLC |
| Tamarisa | The impact of
chemotherapy sequence on survival in node-positive invasive lobular carcinoma | J Surg Onco | 2019 | Retrospective | Clinicopathological | Chemotherapy |
| Thomas | Invasive lobular breast
cancer: A review of pathogenesis, diagnosis, management, and future
directions of early stage disease | Semin Oncol | 2019 | Review | Clinicopathological | Neoadjuvant Therapy |
| Thornton | Neoadjuvant Endocrine
Therapy Versus Neoadjuvant Chemotherapy in Node-Positive Invasive Lobular
Carcinoma | Ann Surg Oncol | 2019 | Retrospective | Clinicopathological | Neoadjuvent Therapy Response |
| Walsh | BET Inhibition as a
Rational Therapeutic Strategy for Invasive Lobular Breast Cancer. | Clin Can Res | 2019 | Laboratory Research | Cancer Biology | Novel therapeutics |
| Williams | Differences in
race, molecular and tumor characteristics among women diagnosed with invasive
ductal and lobular breast carcinomas | Cancer Causes | 2019 | Retrospective | Clinicopathological | Racial Differences in ILC vs IDC |
| Xicola | Clinical features and
cancer risk in families with pathogenic CDH1 variants irrespective of
clinical criteria | J Med Genet | 2019 | Retrospective | Clinicopathological | Genetic basis of ILC |
| Adachi | Comparison of sentinel lymph node biopsy between invasive lobular carcinoma and invasive ductal carcinoma | Breast Cancer | 2018 | Retrospective | Surgery | Sentinal Lymph Node biopsy |
| An | Cdh1 and Pik3ca Mutations Cooperate to Induce Immune-Related Invasive Lobular Carcinoma of the Breast | Cell Reports | 2018 | Laboratory Research | Genomics | Lab Models |
| Bajrami | E-cadherin/ROS1 inhibitor synthetic lethality in breast cancer | Cancer Disc | 2018 | Lab Research | Cancer Biology | E-cadherin |
| Bruner | Loss of E-Cadherin-Dependent Cell–Cell Adhesion and the Development and Progression of Cancer | CSH Perspectives | 2018 | Review | Cancer Biology | E-cadherin |
| Chen | 21-gene recurrence score and adjuvant chemotherapy decisions in patients with invasive lobular breast cancer | Biomarkers in Medicine | 2018 | Retrospective | Genomics | Prognostic Biomarkers |
| Corso | Hereditary lobular breast cancer with an emphasis on E-cadherin genetic defect | J Med Genet | 2018 | Review | Hereditary breast cancer | Germline CDH1 mutation |
| Da Ros | HER2-positive lobular versus ductal carcinoma of the breast: pattern of first recurrence and molecular insights. | Clin Breast Cancer | 2018 | Retrospective | Clinicopathological | Her2+ ILC |
| de groot | αE-catenin is a candidate tumor suppressor for the development of E-cadherin-expressing lobular-type breast cancer | J Pathology | 2018 | Lab Research | Cancer Biology | E-cadherin |
| Desmedt | Immune Infiltration in Invasive Lobular Breast Cancer | J Natl Cancer Inst. | 2018 | Retrospective | Cancer biology | Immunology |
| Ditchi | Low risk of invasive lobular carcinoma of the breast in carriers of BRCA1 and TP53 (Li-Fraumeni syndrome) germline mutations | Breast Journal | 2018 | Retrospective | Hereditary breast cancer | BRCA / p53 mutation |
| Donaldson | Breast cancer risk associated with atypical hyperplasia and lobular carcinoma in situ initially diagnosed on core-needle biopsy | Cancer | 2018 | Retrospective | Risk Factors | LCIS/Hyperplasia |
| Du | Key regulators of lipid metabolism drive endocrine resistance in invasive lobular breast cancer | Breast Cancer Research | 2018 | Lab Research | Cancer biology | Endocrine Resistance |
| Guven | Sentinel Lymph
Node Metastasis in Invasive Lobular Carcinoma of the Breast | European Journal Br Helath | 2018 | Retrospective | Metastasis | Lymph Node Invasion |
| Ha | Breast MR Imaging
before Surgery: Outcomes in Patients with Invasive Lobular Carcinoma by Using
Propensity Score Matching | Radiology | 2018 | Retrospective | Imaging | MRI |
| Liao | The
Clinicopathological Features and Survival Outcomes of Different Histological
Subtypes in Triple-negative Breast Cancer | J Cancer | 2018 | Retrospective | Clinicopathological | Triple-negative ILC |
| Mamtani | Lobular Breast Cancer
Different Disease, Different Algorithms | Surgical Oncol Cinics | 2018 | Review | Clinicopathological | Genomics of ILC |
McCart
Reed | Mixed
ductal-lobular carcinomas: evidence for progression from ductal to lobular
morphology | J Pathology | 2018 | Retrospective | Cancer biology | Mixed ILC/IDC |
| Metzger-Filho | Mixed Invasive
Ductal and Lobular Carcinoma of the Breast: Prognosis and the Importance of
Histologic Grade | The Oncologist | 2018 | Retrospective | Clinicopathological | Mixed ILC/IDC |
| Montagna | Lobular Metastatic
Breast Cancer Patients With Gastrointestinal Involvement: Features and
Outcomes | Clinical Breast Cancer | 2018 | Retrospective | Metastasis | Metastatic Sites |
| Mukhtar | Breast Conservation and
Negative Margins in Invasive Lobular Carcinoma: The Impact of Oncoplastic
Surgery and Shave Margins in 358 Patients | Annals of Surgical Oncol | 2018 | Retrospective | Surgery | Surgical methods |
| Nagle | Loss of
E-cadherin Enhances IGF1–IGF1R Pathway Activation and Sensitizes Breast
Cancers to Anti-IGF1R/InsR Inhibitors | Clinical Cancer Research | 2018 | Laboratory Research | Cancer biology | Cell signaling |
| Oesterreich | Opening the
Door for Immune Oncology Studies in Invasive Lobular Breast Cancer | J Natl Cancer Inst. | 2018 | Editorial | Cancer biology | Immunology |
| Patel | Value Added of
Preoperative Contrast-Enhanced Digital Mammography in Patients With Invasive
Lobular Carcinoma of the Breast | Clinical Breast Cancer | 2018 | Retrospective | Imaging | Mammography methods |
| Perez-Garcia | Efficacy of Single-Agent
Chemotherapy for Patients with Advanced Invasive LobularCarcinoma | The Oncologist | 2018 | Retrospective | Clinicopathological | Chemotherapy |
| Phalak | Supplemental ultrasound
screening in patients with a history of lobular neoplasia | The Breast Journal | 2018 | Retrospective | Imaging | Lobular Neoplasia |
| Sokol | Loss of function
of NF1 is a mechanism of acquired resistance to endocrine therapy in lobular
breast cancer | Ann Oncol | 2018 | Lab Research | Genomics | Endocrine Resistance |
| Stires | Integrated
Molecular Analysis of Tamoxifen-Resistant Invasive Lobular Breast Cancer
Cells Identifies MAPK and GRM/mGluR Signaling as Therapeutic Vulnerabilities | Mol Cell Endocrin | 2018 | Lab Research | Cell Signaling | Endocrine Resistance |
| Strasser-Weippl | Outcomes in women with
invasive ductal or invasive lobular early stage breast cancer treated with
anastrozole or exemestane | European Journal of Cancer | 2018 | Retrospective | Clinicopathological | Endocrine Therapy |
| Tasdemir | Comprehensive
phenotypic characterization of human invasive lobular carcinoma cell lines in
2D and 3D cultures | Cancer Resarch | 2018 | Lab Research | Cancer biology | Lab models |
| Teo | E-cadherin loss
induces targetable autocrine activation of growth factor signalling in
lobular breast cancer | Scientific Reports | 2018 | Lab Research | Cancer biology | Cell signaling |
| Wang | The Distribution
and Outcomes of the 21-Gene Recurrence Score in T1-T2N0 Estrogen
Receptor-Positive Breast Cancer With Different Histologic Subtypes | Frontiers in Genetics | 2018 | Retrospective | Genomics | Prognostic Biomarkers |
| Wen | Lobular Cancer in Situ | Surg Pathol Clin | 2018 | Retrospective | Clinicopathological | Risk Factors |
| Wong | Evaluating the Impact of
Breast Density on Preoperative MRI in Invasive Lobular Carcinoma | J Am Coll Surg | 2018 | Retrospective | Imaging | MRI |
| Baglia | Alcohol Intake and Risk of Breast Cancer by Histologic Subtype and Estrogen Receptor Status Among Women Aged 55 to 74 Years | Hormones and Cancer | 2017 | Retrospective | Risk Factors | Alcohol use |
| Chen | Invasive lobular carcinoma of the breast: A special histological type compared with invasive ductal carcinoma | PLOS One | 2017 | Retrospective | Clinicopathological | Prognosis |
| Christgen | Subclonal analysis in a lobular breast cancer with classical and solid growth pattern mimicking a solidâ€papillary carcinoma | J Patho Clin Res | 2017 | Case Report | Genomics | Papillary Carcinoma |
| Costarelli | Pleomorphic lobular carcinoma: is it more similar to a classic lobular cancer or to a high-grade ductal cancer? | Breast Cancer | 2017 | Retrospective | Cancer biology | Pleomorphic ILC |
| Felts | An Analysis of Oncotype DX Recurrence Scores and Clinicopathologic Characteristics in Invasive Lobular Breast Cancer. | Breast j | 2017 | Retrospective | Genomics | Prognostic Biomarkers |
| Harrell | Estrogen induces
c-Kit and an aggressive phenotype in a model of invasive lobular breast
cancer | Oncogeniesis | 2017 | Lab Research | Cancer Biology | Estrogen signaling |
| Houssami | Meta-analysis of
pre-operative magnetic resonance imaging (MRI) and surgical treatment for
breast cancer | Breast Canc Res Treat | 2017 | Review | Imaging | MRI |
| Inoue | Specific sites of
metastases in invasive lobular carcinoma: a retrospective cohort study of
metastatic breast cancer | Breast Cancer | 2017 | Retrospective | Metastasis | Metastatic Sites |
| Kizy | Impact of the 21-gene
recurrence score on outcome in patients with invasive lobular carcinoma of
the breast | Breast Cancer Res | 2017 | Retrospective | Genomics | Prognostic Biomarkers |
| Lien | Frequent alterations of
HER2 through mutation, amplification, or overexpression in pleomorphic
lobular carcinoma of the breast. | Breast Canc Res Treat | 2017 | Retrospective | Genomics | HER2+ and mutations in PLC |
| Marmor | Relative
Effectiveness of Adjuvant Chemotherapy for Invasive Lobular Compared With
Invasive Ductal Carcinoma of the Breast | Cancer | 2017 | Retrospective | Clinicopathological | Chemotherapy |
| Mathew | Distinct Pattern
of Metastases in Patients with Invasive Lobular Carcinoma of the Breast | Geburtshilfe Frauenheilkd | 2017 | Retrospective | Metastasis | Metastatic Sites |
| Raap | Lobular carcinoma in
situ and invasive lobular breast cancer are characterized by enhanced
expression of transcription factor AP-2β. | Lab Invest | 2017 | Lab Research | Cancer Biology | Genomics of ILC |
| Sahin | Invasive Pleomorphic
Lobular Histology Is an Adverse Prognostic Factor on Survival in Patients
with Breast Cancer | Am Surg | 2017 | Retrospective | Clinicopathological | Pleomorphic ILC |
| Senger | Invasive lobular
carcinoma of the male breast – a systematic review with an illustrative
case study | Breast Cancer | 2017 | Case Report | Clinicopathological | Male ILC |
| Shah | PIK3CA mutations
are common in lobular carcinoma in situ, but are not a biomarker of
progression | Breast Cancer Res | 2017 | Retrospective | Genomics | PIK3CA mutations in LCIS |
| Ulaner | Prospective Clinical
Trial of 18F-Fluciclovine PET/CT for Determining the Response to Neoadjuvant
Therapy in IDC and ILC | Journal of Nuclear Medicine | 2017 | Prospective | Imaging | 18 F-Fluciclovine PET/CT |
| Venema | 18F-FES PET Has Added
Value in Staging and Therapy Decision Making in Patients With Disseminated
Lobular Breast Cancer. | Clin Nucl Med | 2017 | Laboratory Research | Imaging | FES PET |
| Xiao | Mixed invasive
ductal and lobular carcinoma has distinct clinical features and predicts
worse prognosis when stratified by estrogen receptor status | Scientific reports | 2017 | Retrospective | Clinicopathological | Mixed IDC/ILC |
| Abreu | Invasive lobular carcinoma: a rare presentation in the male breast | BMJ Case report | 2016 | Case Report | Clinicopathological | Male ILC |
| Adachi | Comparison of clinical outcomes between luminal invasive ductal carcinoma and luminal invasive lobular carcinoma | BMC Cancer | 2016 | Retrospective | Clinicopathological | Prognosis |
| Barroso-Sousa | Differences between invasive lobular and invasive ductal carcinoma of the breast: results and therapeutic implications | Adv Med Onc | 2016 | Review | Clinicopathological | Therapy Response and Resistance |
| Beumer | Prognostic Value of MammaPrint® in Invasive Lobular Breast Cancer | Biomark Insights | 2016 | Retrospective | Clinicopathological | Prognostic Biomarkers |
| Christgen | Lobular breast cancer: Clinical, molecular and morphological characteristics | Pathology | 2016 | Review | Cancer biology | Pathology |
| Corso | CDH1 germline mutations and hereditary lobular breast cancer. | Fam Cancer | 2016 | Review | Hereditary breast cancer | Germline CDH1 mutation |
| Deniziat | ERBB2 mutations associated with solid variant of high-grade invasive lobular breast carcinomas | Oncotarget | 2016 | Retrospective | Genomics | ERBB2(HER2) Somatic Mutations |
| Desmedt | Genomic Characterization of Primary Invasive Lobular Breast Cancer | Journal of Clinical Oncology | 2016 | Lab Research | Genomics | Mutations in ILC |
| Hornsveld | Restraining
FOXO3-dependent transcriptional BMF activation underpins tumour growth and
metastasis of E-cadherin-negative breast cancer | Cell Death Diff | 2016 | Lab Research | Cancer Biology | Metastasis /E-cadherin |
| Langlands | Contralateral breast
cancer: incidence according to ductal or lobular phenotype of the primary | Clinical Radiology | 2016 | Retrospective | Clinicopathological | Contralateral Breast Cancer |
| Michaut | Integration of
genomic, transcriptomic and proteomic data identifies two biologically
distinct subtypes of invasive lobular breast cancer | Sci Rep | 2016 | Lab Research | Genomics | Genetic basis of ILC |
| Sikora | WNT4 mediates
estrogen receptor signaling and endocrine resistance in invasive lobular
carcinoma cell lines | Breast Cancer Res | 2016 | Lab Research | Cancer biology | Endocrine response and resistance |
| Sledge | Collective
Wisdom: Lobular Carcinoma of the Breast | ASCO | 2016 | Review | Cancer biology | Therapy response and resistance |
| Tenhagen | p120-Catenin Is
Critical for the Development of Invasive Lobular Carcinoma in Mice | J Mamm Gland Biol Neo | 2016 | Lab Research | Cancer Biology | P120 Catenin |
| Truin | Differences in
Response and Surgical Management with Neoadjuvant Chemotherapy in Invasive
Lobular Versus Ductal Breast Cancer | Annals of Surgical Oncol | 2016 | Retrospective | Clinicopathological | Neoadjuvent Chemotherapy |
| Bertozzi | Prevalence, risk factors, and prognosis of peritoneal metastasis from breast cancer | Springer Plus | 2015 | Retrospective | Metastasis | Peritoneal Metastasis |
| Christgen | Lobular breast cancer: molecular basis, mouse and cellular models | Breast Cancer Res | 2015 | Review | Cancer biology | ILC Models |
| Ciriello | Comprehensive Molecular Portraits of Invasive Lobular Breast Cancer | Cell | 2015 | Lab Research | Genomics | Genetic basis of ILC |
| Dashevsky | Appearance of untreated bone metastases from breast cancer on FDG PET/CT: Importance of histologic subtype | Eur J Nucl Med Mol Imaging | 2015 | Retrospective | Imaging | Bone Metastases |
| Dossus | Lobular breast cancer: incidence and genetic and non-genetic risk factors | Breast Cancer Research | 2015 | Review | Risk Factors | Incidence |
| Engstrom | Invasive lobular breast cancer: the prognostic impact of histopathological grade, E-cadherin and molecular subtypes | Histopathology | 2015 | Retrospective | Clinicopathological | Prognosis |
| Hansford | Hereditary
Diffuse Gastric Cancer Syndrome -CDH1 Mutations and Beyond | Jama Oncol | 2015 | Retrospective | Hereditary breast cancer | Genetic CDH1 mutation |
| Hogan | Comparison of
18F-FDG PET/CT for Systemic Staging of Newly Diagnosed Invasive Lobular
Carcinoma Versus Invasive Ductal Carcinoma | J Nucl Med | 2015 | Retrospective | Imaging | FDG PET/CT |
| Jacobs | Issues Affecting the
Loco-regional and Systemic Management of Patients with Invasive Lobular
Carcinoma of the Breast | The Breast Journal | 2015 | Review | Clinicopathological | Therapy Response and Resistance |
| Johnson | Lobular breast cancer
series: imaging | Breast Cancer Res | 2015 | Review | Imaging | Imaging Modalities |
| Logan | Molecular
drivers of lobular carcinoma in situ | Breast Cancer Res | 2015 | Review | Cancer biology | LCIS |
| Lokadasan | Metastatic
lobular carcinoma of breast mimics primary cervix carcinoma: two case reports
and a review of the literature | ecancermedicalscience | 2015 | Case Report | Metastasis | Cervical Metastasis |
McCart
Reed | An epithelial to mesenchymal
transition programme does not usually drive the phenotype of invasive lobular
carcinomas | J Pathology | 2015 | Lab Research | Cancer Biology | E-Cadherin |
McCart
Reed | Invasive lobular
carcinoma of the breast: morphology, biomarkers and Õomics | Breast Cancer Research | 2015 | Review | Cancer biology | Genomics |
| Metzger-Filho | Relative
Effectiveness of Letrozole Compared With Tamoxifen for Patients With Lobular
Carcinoma in the BIG 1-98 Trial | Journal of Clinical Oncology | 2015 | Retrospective | Clinicopathological | Endocrine Therapy |
| Raap | High frequency
of lobular breast cancer in distant metastases to the orbit | Cancer Med | 2015 | Retrospective | Metastasis | Oribital Metastasis |
| Switzer | Case
series of 21 patients with extrahepatic metastatic lobular breast carcinoma
to the gastrointestinal tract | Cancer Treat Comm | 2015 | Case Report | Metastasis | GI Metastasis |
| van de Ven | Nuclear
p120-catenin regulates the anoikis resistance of mouse lobular breast cancer
cells through Kaiso-dependent Wnt11 expression | Dis Model Mech | 2015 | Lab Research | Cancer Biology | P120 Catenin |
van der
Post | Hereditary
diffuse gastric cancer: updated clinical guidelines with an emphasis on
germline CDH1 mutation carriers | J Med Genet | 2015 | Review | Risk Factors | Hereditary CDH1 Mutation |
| Arthur | Molecular Changes in Lobular Breast Cancers in Response to Endocrine Therapy | Cancer Res | 2014 | Retrospective | Genomics | Endocrine Therapy |
| Guiu | Invasive lobular breast
cancer and its variants: how special are they for systemic therapy decisions | Crit Rev Onco Hematology | 2014 | Review | Clinicopathological | Therapy Response and Resistance |
| He | Distant
Metastatic Disease Manifestations in Infiltrating Lobular Carcinoma of the
Breast | AJR | 2014 | Review | Metastasis | Metastatic Sites |
| Narbe | Invasive lobular
carcinoma of the breast: long-term prognostic value of Ki67 and histological
grade, alone and in combination with estrogen receptor | Springer Plus | 2014 | Retrospective | Clinicopathological | Prognosis/Ki67 |
| Olivera | Evolving
concepts in breast lobular neoplasia and invasive lobular carcinoma, and
their impact on imaging methods | Insights Imaging | 2014 | Review | Imaging | Imaging modalities |
| Sawyer | Genetic
Predisposition to In Situ and Invasive Lobular Carcinoma of the Breast | PLOS | 2014 | Retrospective | Genomics | Genetic Basis of ILC/LCIS |
| Sikora | Invasive lobular
carcinoma cell lines are characterized by unique estrogen-mediated gene
expression patterns and altered tamoxifen response | Cancer Resarch | 2014 | Lab Research | Cancer biology | Endocrine response and resistance |
| Christgen | Oncogenic PIK3CA Mutations in Lobular Breast Cancer Progression | Genes Chromosones Cancer | 2013 | Retrospective | Genomics | PIK3CA Mutations |
| Delpech | Clinical benefit from neoadjuvant chemotherapy in oestrogen receptor-positive invasive ductal and lobular carcinomas | British Journal of Cancer | 2013 | Retrospective | Clinicopathological | Chemotherapy |
| Ishida | Pleomorphic
lobular carcinoma in a male breast: a case report with review of the
literature | Int J Clin Exp Pathol | 2013 | Case Report | Clinicopathological | Male ILC |
| Korhonen | The
impact of lobular and ductal breast cancer histology on the metastatic
behavior and long term survival of breast cancer patients | The Breast | 2013 | Retrospective | Clinicopathological | Metastasis |
| Metzger-Filho | Magnitude of
trastuzumab benefit in patients with HER2-positive, invasive lobular breast
carcinoma: results from the HERA trial | Journal of Clinical Oncology | 2013 | Retrospective | Clinicopathological | HER2+ ILC |
| Metzger-Filho | Genomic grade adds
prognostic value in invasive lobular carcinoma | Ann Onc | 2013 | Retrospective | Genomics | Gene Signatures |
| Moten | Characterizing lobular
carcinoma of the male breast using the SEER database. | J surg Res | 2013 | Retrospective | Clinicopathological | Male ILC |
| Ross | Relapsed
Classic E-Cadherin (CDH1)–Mutated Invasive Lobular Breast Cancer Shows
a High Frequency of HER2 (ERBB2) Gene Mutations | Clinical Cancer Research | 2013 | Retrospective | Genomics | HER2(ERBB2) Mutation in iLC |
| Vlug | Nuclear
localization of the transcriptional coactivator YAP is associated with
invasive lobular breast cancer | Cell Oncol | 2013 | Laboratory Research | Cancer Biology | Cell Signaling |
| Brunello | FGFR-1 amplification in metastatic lymph-nodal and haematogenous lobular breast carcinoma | J Exp Clin Cancer Res | 2012 | Retrospective | Genomics | FGFR1 mutation |
| Carcoforo | Infiltrating Lobular Carcinoma of the Breast Presenting as Gastrointestinal Obstruction: A Mini Review | Journal of Cancer | 2012 | Case Report | Metastasis | GI Metastasis |
| Gainer | Invasive Lobular
Carcinoma Predicts Micrometastasis in Breast Cancer | Journal or Surgical Research | 2012 | Lab Research | Cancer biology | Metastasis |
| Iorfida | Invasive lobular breast
cancer: subtypes and outcome | Breast Cancer Res Treat | 2012 | Retrospective | Clinicopathological | Prognosis |
| Sikora | Invasive lobular
carcinoma of the breast: Patient response to systemic endocrine therapy and
hormone response in model systems | Steroids | 2012 | Review | Cancer biology | Endocrine Resistance |
van de
Water | Influence
of semi-quantitative oestrogen receptor expression on adjuvant endocrine
therapy efficacy in ductal and lobular breast cancer | Eur J Cancer | 2012 | Retrospective | Clinicopathological | Adjuvent Endocrine Therapy |
| Derksen | Mammary-specific inactivation of E-cadherin and p53 impairs functional gland development and leads to pleomorphic invasive lobular carcinoma in mice | Dis Model Mech | 2011 | Lab Research | Cancer Biology | ILC Models
|
| Dixon | Invasive lobular carcinoma: response to neoadjuvant letrozole therapy | Breast Cancer Res Treat | 2011 | Retrospective | Clinicopathological | Endocrine Resistance |
| Patel | CT, MRI and PET imaging in peritoneal malignancy | Cancer Imaging | 2011 | Review | Imaging | Peritoneal Metastasis |
| Schackmann | Cytosolic
p120-catenin regulates growth of metastatic lobular carcinoma through
Rock1-mediated anoikis resistance | J Clin Invest | 2011 | Lab Research | Cancer Biology | P120-Catenin |
| Yu | Classical-type
invasive lobular carcinoma with HER2 overexpression: clinical, histologic,
and hormone receptor characteristics | Am J Clinical Path | 2011 | Case Report | Cancer biology | HER2 in ILC |
| Anwar | Invasive lobular carcinoma of the breast: Should this be regarded as a chronic disease? | Intl J Surg | 2010 | Retrospective | Clinicopathological | Prognosis |
| Phipps | Risk factors for ductal, lobular, and mixed ductal-lobular breast cancer in a screening population | Cancer Epidemiol Biomarkers Prev | 2010 | Retrospective | Clinicopathological | Risk Factors |
| Lopez | Invasive Lobular
Carcinoma of the Breast: Spectrum of Mammo- graphic, US, and MR Imaging
Findings | Radiographics | 2009 | Review | Imaging | Imaging modalities |
| Vargas | Pleomorphic lobular
carcinoma of the breast: molecular pathology and clinical impact | Future Oncol | 2009 | Review | Genomics | Pleomorphic ILC |
| Mann | MRI compared to
conventional diagnostic work-up in the detection and evaluation of invasive
lobular carcinoma of the breast | Breast Cancer Res | 2008 | Review | Imaging | MRI |
| Orvieto | Clinicopathologic
characteristics of invasive lobular carcinoma of the breast | Cancer | 2008 | Retrospective | Clinicopathological | Prognosis |
| Pestalozzi | Distinct
Clinical and Prognostic Features of Infiltrating Lobular Carcinoma of the
Breast: Combined Results of 15 International clinical trials | J Clin Oncol | 2008 | Retrospective | Clinicopathological | Prognosis |
| Rakha | Invasive lobular
carcinoma of the breast: response to hormonal therapy and outcomes | Eur J Cancer | 2008 | Retrospective | Clinicopathological | Adjuvent Endocrine Therapy |
| Riggins | ERRγ
mediates Tamoxifen resistance in novel models of invasive lobular breast
cancer | Cancer Res | 2008 | Lab Research | Cancer biology | Endocrine Resistance |
| Shrader | Hereditary
diffuse gastric cancer: association with lobular breast cancer | Fam Cancer | 2008 | Case Report | Clinicopathological | Herditary CDH1 mutation |
| Dabbs | Lobular versus ductal breast neoplasms: the diagnostic utility of p120 catenin | Am J Surg Path | 2007 | Retrospective | Clinicopathological | P120-Catenin |
| Xin | A review of invasive lobular
carcinoma of the breast: Should it be treated like invasive ductal carcinoma? | Integr Cancer Sci Therapy | 2007 | Review | Clinicopathological | Prognosis |
| Derkson | Somatic inactivation of E-cadherin and p53 in mice leads to metastatic lobular mammary carcinoma through induction of anoikis resistance and angiogenesis | Cancer Cell | 2006 | Lab Research | Cancer Biology | ILC Models |
| Reis-Filho | FGFR1
Emerges as a Potential Therapeutic Target for Lobular Breast Carcinomas | Clin Can Res | 2006 | Retrospective | Genomics | FGFR1 mutation |
| Stange | High-Resolution
Genomic Profiling Reveals Association of Chromosomal Aberrations on 1q and
16p with Histologic and Genetic Subgroups of IBC cell lines | Clinical Cancer Research | 2006 | Retrospective | Genomics | Genomics of ILC |
| Talman | Invasive
lobular breast cancer. Prognostic significance of histological malignancy
grading | Acta Onc | 2006 | Retrospective | Clinicopathological | Prognosis |
| Christofanilli | Invasive Lobular Carcinoma Classic Type: Response to Primary Chemotherapy and Survival Outcomes | Journal of Clinical Oncology | 2005 | Retrospective | Clinicopathological | Chemotherapy |
| Singletary | Treatment Trends
in Early-Stage Invasive Lobular Carcinoma | Ann Surgery | 2005 | Retrospective | Surgery | Surgical Methods |
| Arpino | Infiltrating lobular carcinoma of the breast: tumor characteristics and clinical outcome | Breast Cancer Research | 2004 | Retrospective | Clinicopathological | Characteristics of ILC |
| Berg | Diagnostic accuracy of mammography, clinical examination, US, and MR imaging in preoperative assessment of breast cancer | Radiology | 2004 | Retrospective | Imaging | Imaging Methods |
| Mathieu | The poor responsiveness
of infiltrating lobular breast carcinomas to neoadjuvant chemotherapy can be
explained by their biological profile | Eur J Cancer | 2004 | Retrospective | Clinicopathological | Chemotherapy |
| Selinko | Role of sonography in
diagnosing and staging invasive lobular carcinoma | J Clin Ultrasound | 2004 | Retrospective | Imaging | Imaging Methods |
| Li | Hormone replacement
therapy in relation to risk of lobular and ductal breast carcinoma in
middle-aged women. | Cancer | 2000 | Retrospective | Risk Factors | Hormone Replacement Therapy |
| Li | Changing Incidence Rate
of Invasive Lobular Breast Carcinoma among Older Women | Cancer | 2000 | Retrospective | Risk Factors | Incidence |
| Winston | Metastatic
Lobular Carcinoma of the Breast: Patterns of Spread in the Chest, Abdomen,
and Pelvis on CT | AJR | 2000 | Retrospective | Metastasis | Metastatic sites |